Depression treatment in clinical settings includes self-adjustment, psychotherapy, medication, and physical therapy. Patients with mild depression can base their treatment on self-adjustment, which includes exercising, distracting attention, talking to others, etc. Psychotherapy, especially cognitive behavioral therapy, is recommended as the first choice of treatment. It helps patients identify automatic thoughts and reconstruct the cognitive irrationality system among other methods. Furthermore, patients with moderate to severe depression are primarily treated with medication, particularly with serotonin reuptake inhibitors such as paroxetine, sertraline, and fluoxetine, which are commonly used in clinical settings. Additionally, physical therapy mainly involves non-convulsive electroshock and transcranial magnetic stimulation as major treatment methods. (Specific medications should be used under the guidance of a physician.)