Does hypothyroidism lead to thyroid cancer?

Written by Gan Jun
Endocrinology
Updated on December 17, 2024
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Hypothyroidism and thyroid cancer are two different types of thyroid diseases; hypothyroidism does not cause thyroid cancer, and there is no necessary connection between the two. Hypothyroidism refers to a decrease in thyroid function levels, caused by abnormalities in the secretion and synthesis functions of the thyroid, closely related to disorders of the endocrine system. In contrast, thyroid cancer is a change in tissue nature due to malignant transformation in thyroid tissue cells, it is not related to the thyroid's endocrine functions, and currently, there is no research indicating that hypothyroidism increases the likelihood of developing thyroid cancer. Patients with thyroid diseases should undergo dynamic thyroid ultrasonography and monitoring of thyroid function to further clarify their condition.

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Written by Gong Chun
Oncology
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How is thyroid cancer caused?

The causes of thyroid cancer are similar to those of most other malignancies. The etiology of thyroid cancer is not yet clear, but some factors are found to be associated with its occurrence: The first is neck radiation. The thyroid is an endocrine organ, sensitive to radiation. Radiation exposure can potentially cause thyroid cells to become cancerous, especially in those who received high doses of neck radiation in childhood and are more susceptible to thyroid cancer. The second factor is genetics; some thyroid cancers have a clear genetic predisposition, the most typical being medullary thyroid cancer. The third point is that the rapid increase in the incidence rate of thyroid cancer is partly due to the advancement in early diagnostic techniques, allowing for the detection of many early-stage lesions. Of course, iodine intake has already been shown to be related to some benign thyroid conditions. However, its relationship with thyroid cancer requires further study.

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Can thyroid cancer cause an itchy throat and cough?

Patients with thyroid cancer may experience symptoms such as throat itching and coughing. The causes can be considered from the following aspects: Firstly, thyroid cancer tends to metastasize to the lungs through the bloodstream. Once lung metastasis occurs, respiratory symptoms will appear, including throat itching and coughing. Additionally, these symptoms may also arise from a decrease in immunity following chemotherapy, radiotherapy, and surgical treatments for thyroid cancer, leading to concurrent lung infections. Thirdly, some patients with thyroid cancer may have invasion of nearby organs, such as the esophagus or airways, which can also lead to symptoms of throat itching and coughing. In terms of treatment, apart from symptomatic drug therapy, it is paramount to administer systemic anti-tumor treatments. Effective control of thyroid cancer is essential to alleviate these clinical symptoms.

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What department should thyroid cancer see?

Firstly, thyroid cancer is the most common malignant tumor in the neck area. Therefore, it is recommended to consult with the most professional oncology department for diagnosis and treatment when the disease occurs. If thyroid cancer is operable, surgery can be performed by the head and neck surgery department. After surgical treatment, if radiotherapy and chemotherapy are needed, it is still recommended to see an oncologist for treatment and specific therapies. Thus, different departments may be consulted during different stages of the disease, but the primary recommendation is still to seek treatment from the oncology department.

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How to treat differentiated thyroid cancer

The so-called differentiated thyroid cancers include two types: papillary and follicular thyroid cancers. Their treatment methods consist of the following: First, surgical treatment is a primary treatment strategy for early-stage differentiated thyroid cancers, involving radical surgical removal. After surgery, some patients need to take medications to supplement thyroid hormones. Secondly, for patients with advanced differentiated thyroid cancers, the main comprehensive treatment measures include radiotherapy and chemotherapy. Additionally, postoperative early-stage patients can also undergo treatment with Iodine-131 to monitor changes in the condition and provide internal radiation treatment to control the progression of the disease. Internal radiation treatment can be performed multiple times.

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Early symptoms of thyroid cancer

In the early stages, most thyroid cancer patients do not exhibit obvious symptoms. A minority of patients may inadvertently find that thyroid nodules grow rapidly and these nodules have slightly limited mobility and mild pain upon palpation. Some patients with medullary thyroid cancer may experience symptoms like facial flushing early on due to abnormal hormone secretion in the body. Additionally, clinical symptoms are not commonly seen in the early stages of thyroid cancer. Only as the disease progresses can symptoms such as neck lumps from regional lymph node metastasis, as well as distant spread, cause clinical symptoms like neck swelling, chest tightness, and difficulty breathing.