Early symptoms of thyroid cancer

Written by Yan Chun
Oncology
Updated on January 21, 2025
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In the early stages, most thyroid cancer patients do not exhibit obvious symptoms. A minority of patients may inadvertently find that thyroid nodules grow rapidly and these nodules have slightly limited mobility and mild pain upon palpation. Some patients with medullary thyroid cancer may experience symptoms like facial flushing early on due to abnormal hormone secretion in the body. Additionally, clinical symptoms are not commonly seen in the early stages of thyroid cancer. Only as the disease progresses can symptoms such as neck lumps from regional lymph node metastasis, as well as distant spread, cause clinical symptoms like neck swelling, chest tightness, and difficulty breathing.

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Written by Gong Chun
Oncology
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Early symptoms of thyroid cancer

Differentiated thyroid cancer often has no symptoms in the early stages, with only incidental palpation of nodules of various sizes and textures on the front of the neck. Some patients may find abnormalities during routine physical examinations through imaging studies, and symptoms may appear only in the later stages. The second point concerns the characteristics of medullary thyroid cancer, which exhibits specific symptoms early on, such as persistent, watery diarrhea. Additionally, this cancer involves an endocrine syndrome, where tumor cells secrete calcitonin and adrenocorticotropic hormone, potentially leading to facial flushing, elevated blood pressure, and reduced blood calcium. This may be associated with other conditions such as pheochromocytoma, multiple mucosal neuromas, and parathyroid adenomas, which can also cause corresponding symptoms.

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Written by Gong Chun
Oncology
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How is thyroid cancer caused?

The causes of thyroid cancer are similar to those of most other malignancies. The etiology of thyroid cancer is not yet clear, but some factors are found to be associated with its occurrence: The first is neck radiation. The thyroid is an endocrine organ, sensitive to radiation. Radiation exposure can potentially cause thyroid cells to become cancerous, especially in those who received high doses of neck radiation in childhood and are more susceptible to thyroid cancer. The second factor is genetics; some thyroid cancers have a clear genetic predisposition, the most typical being medullary thyroid cancer. The third point is that the rapid increase in the incidence rate of thyroid cancer is partly due to the advancement in early diagnostic techniques, allowing for the detection of many early-stage lesions. Of course, iodine intake has already been shown to be related to some benign thyroid conditions. However, its relationship with thyroid cancer requires further study.

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Written by Yan Chun
Oncology
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How to treat differentiated thyroid cancer

The so-called differentiated thyroid cancers include two types: papillary and follicular thyroid cancers. Their treatment methods consist of the following: First, surgical treatment is a primary treatment strategy for early-stage differentiated thyroid cancers, involving radical surgical removal. After surgery, some patients need to take medications to supplement thyroid hormones. Secondly, for patients with advanced differentiated thyroid cancers, the main comprehensive treatment measures include radiotherapy and chemotherapy. Additionally, postoperative early-stage patients can also undergo treatment with Iodine-131 to monitor changes in the condition and provide internal radiation treatment to control the progression of the disease. Internal radiation treatment can be performed multiple times.

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Written by Yan Chun
Oncology
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Can occasional smoking and drinking be okay with thyroid cancer?

Thyroid cancer is a common malignant tumor in the head and neck area, and currently, the exact mechanism and etiological causes of thyroid cancer are not clearly defined in the clinic. However, some research studies indicate that there are certain factors associated with the incidence of thyroid cancer. For example, ionizing radiation, prolonged exposure can lead to the occurrence of thyroid cancer. Both insufficient and excessive iodine intake can lead to a high incidence of thyroid cancer. Genetic factors also play a significant role in the development of thyroid cancer. Excessive smoking and drinking can promote the occurrence of thyroid cancer. Therefore, heavy smoking and drinking are not recommended, but occasional smoking and drinking do not significantly impact the condition of thyroid cancer and are deemed acceptable. Moreover, for patients with thyroid cancer, treatment is primarily surgical, as radiotherapy and chemotherapy are not very sensitive anti-tumor treatments.

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Written by Chen Xie
Endocrinology
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What are the clinical manifestations of thyroid cancer?

For patients with thyroid cancer, the most common clinical manifestation is thyroid nodules, and most patients do not have obvious clinical symptoms, only being incidentally discovered during physical examinations. In rare cases, patients may seek medical attention due to enlarged cervical lymph nodes. As the condition progresses, the neck mass gradually enlarges, becomes firmer, and its mobility decreases during swallowing. In some rapid developments, it may invade surrounding tissues, leading to late-stage symptoms such as hoarseness, difficulty breathing, and difficulty swallowing. When the cervical sympathetic nerve is compressed, it can cause pain in the ears, occipital region, and shoulders. In the case of medullary carcinoma, which can produce serotonin and calcitonin, patients may sometimes experience symptoms such as diarrhea, palpitations, facial flushing, or decreased blood calcium levels.