What causes systemic lupus erythematosus?

Written by Yang Ya Meng
Rheumatology
Updated on October 25, 2024
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Systemic lupus erythematosus mainly has four major causes: The first is related to the environment. Long-term exposure to sunlight, or living in a humid environment, may trigger the onset of systemic lupus erythematosus. Secondly, there is a certain genetic predisposition to systemic lupus erythematosus. If the parents have systemic lupus erythematosus, the probability of their offspring developing the disease is higher. Thirdly, systemic lupus erythematosus is also related to estrogen, which is why, clinically, lupus is more commonly seen in women of childbearing age and less often in men. Systemic lupus erythematosus is also associated with some specific infections, such as bacterial or viral infections, which may trigger a lupus flare-up.

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Can people with systemic lupus erythematosus eat black fungus?

Systemic lupus erythematosus is an autoimmune disease that affects multiple systems and organs. It cannot be cured and can only be managed through medications to control the progression of the disease and delay complications. It commonly occurs in women of childbearing age. In the early stages, when no other organs are damaged, there are no special dietary restrictions and black fungus can be eaten. However, fruits such as figs and bayberries, which are exposed to ultraviolet light for a long period, should be avoided. If the disease affects the kidneys causing damage such as proteinuria and increased creatinine, a diet low in salt, fat, and restricted in high-quality protein is necessary. High-quality protein mainly refers to lean meats and pure milk, and consumption of black fungus should be moderated.

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What to do about hair loss from systemic lupus erythematosus?

Systemic lupus erythematosus is a multi-system, multi-damage autoimmune disease, primarily manifesting in the skin and mucous membranes. Some individuals may also experience low-grade fever and hair loss, even severe hair loss. If treatment has already commenced and hair loss continues during the treatment process, it is necessary to consider whether the medication dosage is insufficient and to consider adjusting the medication dosage. If medication has been discontinued and severe hair loss reoccurs, the first consideration should be whether there is a recurrence of active disease, necessitating a visit to the hospital for tests including a complete blood count, erythrocyte sedimentation rate, C-reactive protein, complement levels, and autoimmune antibodies to comprehensively assess whether the disease has relapsed. If the disease has relapsed, it is necessary to reintroduce steroids, adjust medication dosages, and combine the use of hydroxychloroquine to control the disease. (Specific medications should be used under the guidance of a physician.)

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Written by Yang Ya Meng
Rheumatology
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What should be noted about systemic lupus erythematosus?

Patients with lupus should be cautious about several lifestyle factors. First, they should avoid prolonged exposure to the sun, as ultraviolet rays can potentially trigger the activity of lupus. Second, they should not overexert themselves, as fatigue can also lead to an exacerbation of lupus symptoms. Third, they must strictly avoid infections. Due to the long-term use of corticosteroids and immunosuppressants, lupus patients have reduced immunity, and even a minor infection can become uncontrollable. For lupus patients, lifelong medication is crucial. Commonly used medications include corticosteroids and hydroxychloroquine. If the patient's visceral systems are involved, immunosuppressants may also be required. Additionally, patients should consistently attend regular check-ups at the rheumatology clinic. (Specific medication use should be conducted under the guidance of a doctor.)

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Written by Li Jing
Rheumatology
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Can systemic lupus erythematosus be cured?

Systemic lupus erythematosus is a multi-system autoimmune disease and a chronic condition with an unclear cause, making it incurable. Treatment primarily involves medication to control the progression of the disease, prevent relapse, and delay the onset of complications in other organs. The comprehensive goal of treatment is to manage these aspects. Additionally, exposure to direct sunlight should be avoided, and women should avoid oral contraceptives, as these can trigger active lupus. Furthermore, it's crucial to avoid consuming figs, bayberries, and other fruits that have been exposed to ultraviolet light over a long period, as they can also induce lupus activity.

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Systemic Lupus Erythematosus Symptom Chart

Firstly, systemic lupus erythematosus is a multi-system, multi-organ autoimmune disease that cannot be cured but can only be controlled with medication to slow the progression of the disease and prevent complications. Clinical manifestations are diverse, with most early symptoms typically being atypical, and sometimes not presenting any discomfort at all. Some individuals may experience acute onset, which can include high fever, progressive decline in platelets, and even progressive anemia, all characteristic of the acute phase. Other common symptoms include fever, skin erythema, and even ischemia of the extremities. Some people may experience joint pain, mainly in the finger joints and knee joints, as well as swelling of the lower limbs, chest tightness, and decreased exercise tolerance, which are more typical manifestations.