Does systemic lupus erythematosus affect pregnancy?
Updated on June 24, 2025
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Patients with systemic lupus erythematosus (SLE) can be significantly affected during pregnancy, with some female patients experiencing recurrent miscarriages. These recurrent miscarriages are sometimes associated with antiphospholipid antibody syndrome secondary to lupus, as these patients test positive for anticardiolipin antibodies and lupus anticoagulant, leading to repeated miscarriages. Additionally, patients with systemic lupus erythematosus are particularly prone to triggering disease activity in the six weeks before and after pregnancy, presenting symptoms such as fever, joint pain, and even renal disorders, which leads to the activity of lupus itself, thus preventing the continuation of the pregnancy.
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