What medication is used for systemic lupus erythematosus?

Written by Li Jing
Rheumatology
Updated on September 14, 2024
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Systemic lupus erythematosus is a global autoimmune disease that can involve multiple systems and organs. The cause of the disease is unclear, and it cannot be completely cured; it can only be managed through medication. However, once the condition stabilizes, the medication dosage can be gradually reduced and maintained at a low dose. The preferred treatment is corticosteroids, but if there is damage to other organs, such as pulmonary interstitial fibrosis or renal damage and proteinuria, it is necessary to combine immunosuppressants. This is done to prevent recurrence of the disease and to manage complications that may arise during the reduction of steroids. Additionally, it is crucial to be cautious about sun protection, avoid oral contraceptives, and prevent exposure to cold and overexertion. (Please take medication under the guidance of a doctor.)

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Written by Li Jing
Rheumatology
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Is systemic lupus erythematosus serious?

Firstly, whether systemic lupus erythematosus (SLE) is severe cannot be generalized. It is an autoimmune disease that cannot be completely cured and can cause damage to multiple systems and organs, leading to serious complications. Therefore, it is crucial to conduct a clinical analysis and assess the severity of the condition as mild, moderate, or severe after diagnosis. Furthermore, if severe anemia or a decrease in platelets occurs, the condition is relatively severe, and the presence of oliguria or anuria or central nervous system damage, this is known as lupus crisis. These conditions can be life-threatening, even leading to death. In such cases, the condition is relatively critical, and it is essential to actively treat and control the condition. Once the condition stabilizes, the medication dosage should be gradually reduced to maintain stability.

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Written by Li Jing
Rheumatology
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Systemic lupus erythematosus is a disease.

Firstly, systemic lupus erythematosus is a chronic disease. It is an autoimmune disease that can affect multiple systems and organs and cannot be cured. It can only be controlled over the long term with medication. The goals of comprehensive treatment are to control symptoms, prevent relapses, slow the progression of the disease, and provide symptomatic treatment. Because this disease cannot be cured, it is important to avoid sun exposure, overwork, and getting chilled in daily life to prevent triggering or worsening the condition. Particularly in women, it is crucial to avoid oral contraceptives.

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Written by Yang Ya Meng
Rheumatology
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Is systemic lupus erythematosus serious?

Systemic lupus erythematosus (SLE) can vary in severity. The main criterion for determining whether it is mild or severe is to check whether SLE has involved important visceral organs, such as the lungs, the heart, and most commonly, the kidneys, as well as the most severe form, neuropsychiatric lupus. If a patient shows involvement of the aforementioned visceral systems, then lupus is considered to be relatively severe, and may sometimes even threaten the patient’s life. However, if lupus does not involve the visceral systems, it is considered to be mild.

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Written by Li Jing
Rheumatology
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Systemic Lupus Erythematosus Symptom Chart

Firstly, systemic lupus erythematosus is a multi-system, multi-organ autoimmune disease that cannot be cured but can only be controlled with medication to slow the progression of the disease and prevent complications. Clinical manifestations are diverse, with most early symptoms typically being atypical, and sometimes not presenting any discomfort at all. Some individuals may experience acute onset, which can include high fever, progressive decline in platelets, and even progressive anemia, all characteristic of the acute phase. Other common symptoms include fever, skin erythema, and even ischemia of the extremities. Some people may experience joint pain, mainly in the finger joints and knee joints, as well as swelling of the lower limbs, chest tightness, and decreased exercise tolerance, which are more typical manifestations.

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Written by Li Jing
Rheumatology
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Can people with systemic lupus erythematosus have children?

Firstly, systemic lupus erythematosus is an autoimmune disease of unknown etiology, and it can affect multiple organs including the heart, lungs, kidneys, and gastrointestinal tract. Once diagnosed with systemic lupus erythematosus, it is essential to complete routine urine tests, 24-hour urine protein quantification, chest CT, and other related examinations to fully assess the condition and distinguish between mild, moderate, and severe cases. Treatment plans should be formulated based on the assessment of the condition. If it is purely systemic lupus erythematosus without damage to other organs and the condition is stable with reduced maintenance doses of steroids, then pregnancy can be considered. However, during pregnancy, it is crucial to regularly monitor pulmonary arterial hypertension, pulmonary artery pressure, 24-hour urine protein quantification, and kidney function. If complications such as lupus nephritis occur, treatment decisions should be based on the condition. For instance, if there is an increase in creatinine and significant proteinuria, pregnancy is not recommended as it can exacerbate the burden on the kidneys and lead to further deterioration of kidney function.