Breast cancer chemotherapy regimen

Written by Gong Chun
Oncology
Updated on September 06, 2024
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Breast cancer chemotherapy regimen. Thus, chemotherapy occupies a very important position in the treatment of breast cancer. The commonly used chemotherapy drugs in breast cancer treatment include alkylating agents, such as cyclophosphamide; antimetabolites like fluorouracil, methotrexate, gemcitabine, and capecitabine; anthracyclines, such as doxorubicin and others. In recent years, taxanes, particularly docetaxel, have been used more frequently. Other drugs include mitomycin and cisplatin, among others. However, the specific chemotherapy regimen for breast cancer should be assessed by a professional oncologist. The regimen should consider the pathological stage, pathological type, whether surgery was performed, whether the surgery completely removed the tumor, lymph node metastasis, and other factors to devise a suitable chemotherapy plan. Therefore, it is possible that each individual might have a regimen that is specifically suited to their situation, and not all regimens are suitable for everyone.

Other Voices

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Does breast cancer require chemotherapy?

Not all breast cancer requires chemotherapy, which is just one method in the comprehensive treatment of breast cancer. Comprehensive treatment for breast cancer includes surgery, chemotherapy, radiotherapy, endocrine therapy, biological targeted therapy, and also traditional Chinese medicine treatment. Chemotherapy, in particular, can be described as a double-edged sword that kills both cancerous and normal cells. If the breast cancer is in an early stage, especially if the genetic typing is favorable, there might be an opportunity to forego chemotherapy. However, unfortunately, as of now, a significant portion of breast cancer cases still require chemotherapy. Therefore, it is necessary to communicate with professional doctors and analyze each specific case individually; one cannot generalize the treatment.

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Written by Fan Hong Qiao
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What is invasive breast cancer?

Invasive breast cancer is the most common tumor in women, accounting for 22% of all malignant tumors in females. Invasive breast cancer refers to a malignant tumor where cancer cells have broken through the basement membrane of the breast ducts or lobular alveoli and invaded the interstitium. The vast majority of invasive breast cancers are adenocarcinomas, originating from the epithelial cells of the breast parenchyma, especially from the terminal duct lobular units. Its characteristics include the tumor's infiltration into adjacent tissues and a marked tendency for distant metastasis.

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Written by Liu Liang
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Thymus cancer and breast cancer differences

Thymic cancer, which refers to the malignant tumor that occurs in the thymus, predominantly presents as squamous cell carcinoma. It generally arises in the mediastinum, with clinical symptoms such as chest pain, cough, and breathing difficulties. Breast cancer, on the other hand, refers to the malignant tumor occurring in the breast tissue, with invasive ductal carcinoma being the most common type. Its symptoms often include unintentionally discovered breast lumps, or metastasis to axillary lymph nodes, felt as enlargement of these nodes. Therefore, these two diseases differ in their sites of origin, symptoms, pathological types, and treatments.

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Breast cancer IIA is stage 2.

Breast cancer stage IIa is considered early stage. Breast cancer is classified into stages 0, I, IIa, IIb, III, and IV. Stage III is further divided into IIIa, IIIb, and IIIc. Strictly speaking, breast cancers at stage IIa and earlier are considered early-stage breast cancer, while stage III is considered locally advanced breast cancer, including IIIa, IIIb, and IIIc, and stage IV is considered advanced breast cancer. However, since most operable breast cancers, which include up to stage IIIa (stages 0, I, II, and including IIIa), generally have favorable treatment outcomes, many research institutions and medical organizations in Western countries define all stages up to IIIa as early-stage breast cancer. Therefore, breast cancer stage IIa is classified as early-stage cancer.

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Breast cancer surgical methods

There are many surgical methods for breast cancer, but specifically, they are related to the stage of the disease. Generally speaking, the surgical methods for breast cancer include the following types: The first type is the modified radical mastectomy, which is the most traditional and has the broadest scope of excision. This often involves the complete removal of the breast, and the axilla may be cleared, or a sentinel lymph node biopsy may be performed instead, which is a possibility. The second type of breast cancer surgery is the best, used for early-stage breast cancer, which can preserve the breast, known as breast-conserving surgery. The third method of surgery involves removing all the glandular tissue inside the breast while preserving the skin, nipple, and areola complex, and then reconstructing the breast by placing an implant.