Treatment of Hyperuricemia

Written by Zhang Li
Endocrinology
Updated on May 27, 2025
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Hyperuricemia is becoming increasingly common in today's life, and its treatment is divided into two main aspects: lifestyle interventions and medication treatment.

For lifestyle, the main focus should be on healthy eating, quitting smoking, maintaining regular exercise, and proper weight control. Regarding diet, a strict low-purine diet is essential, especially avoiding the consumption of animal offals, meat broths, seafood, and beer. Additionally, it is important to alkalinize urine, which can be done using substances like baking soda or soda water. Also, ensure to drink plenty of water, maintaining a daily intake of over 2000 milliliters, and control other risk factors that can cause hyperuricemia, such as high cholesterol, high blood pressure, and high blood sugar.

In terms of medication, the choice of drugs should be based on the different causes of hyperuricemia. If it is due to a uric acid excretion disorder, drugs like probenecid may be used. If it is due to an overproduction of uric acid, medications like allopurinol could be considered.

(Please use medication under the guidance of a doctor.)

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Written by Zhang Li
Endocrinology
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Treatment of Hyperuricemia

Hyperuricemia is becoming increasingly common in today's life, and its treatment is divided into two main aspects: lifestyle interventions and medication treatment. For lifestyle, the main focus should be on healthy eating, quitting smoking, maintaining regular exercise, and proper weight control. Regarding diet, a strict low-purine diet is essential, especially avoiding the consumption of animal offals, meat broths, seafood, and beer. Additionally, it is important to alkalinize urine, which can be done using substances like baking soda or soda water. Also, ensure to drink plenty of water, maintaining a daily intake of over 2000 milliliters, and control other risk factors that can cause hyperuricemia, such as high cholesterol, high blood pressure, and high blood sugar. In terms of medication, the choice of drugs should be based on the different causes of hyperuricemia. If it is due to a uric acid excretion disorder, drugs like probenecid may be used. If it is due to an overproduction of uric acid, medications like allopurinol could be considered. (Please use medication under the guidance of a doctor.)

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Written by Lin Xiang Dong
Endocrinology
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Causes of hyperuricemia

Hyperuricemia is divided into primary hyperuricemia and secondary hyperuricemia. Primary hyperuricemia is mainly due to a disorder in the metabolism of purines in the body, leading to excessive production of uric acid, which in turn causes hyperuricemia. Prolonged duration can greatly increase the risk of gout. Secondary hyperuricemia refers to hyperuricemia caused by excessive production or excretion obstacles due to some common diseases, the most common being chronic renal failure or some tumors, etc.

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Written by Lin Xiang Dong
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Hyperuricemia standards

The diagnostic criteria for hyperuricemia specify that under normal purine diet conditions, if the fasting serum uric acid level on non-consecutive days exceeds 420 micromoles/liter for males and 360 micromoles/liter for females, hyperuricemia can be diagnosed. Hyperuricemia is typically classified into primary hyperuricemia and secondary hyperuricemia, with most patients showing no clear clinical symptoms.

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Written by Li Hui Zhi
Endocrinology
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What are the harms of hyperuricemia?

What are the dangers of hyperuricemia? First, it primarily causes gouty arthritis, characterized by redness, swelling, heat, and pain in certain joints, along with limited movement. For some people, the pain can be extremely unbearable. Second, long-term high levels of uric acid can damage the kidneys, leading to impaired kidney function. Third, these purines deposit in the joints forming gout stones, further affecting the function of these joints and reducing the quality of life. Therefore, it is important to treat hyperuricemia early to prevent complications.

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Written by Lin Xiang Dong
Endocrinology
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Hyperuricemia Typing

Hyperuricemia can usually be divided into two types: primary hyperuricemia and secondary hyperuricemia. The first type, primary hyperuricemia, is mainly due to congenital purine metabolic disorders, leading to excessive production of uric acid in the body, which then causes hyperuricemia. Secondary hyperuricemia is caused by a variety of acute and chronic diseases, such as common chronic renal failure, and hematological tumors, among others.