How is hyperuricemia treated?

Written by Chen Xie
Endocrinology
Updated on September 01, 2024
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The treatment of hyperuricemia mainly includes the following points: 1. Improve lifestyle primarily, including a low-purine diet, appropriate exercise, smoking cessation, and increased water intake. 2. Alkalize urine using sodium bicarbonate to maintain urine pH value between 6.2 and 6.9, which facilitates the excretion of uric acid. 3. Avoid drugs that increase uric acid levels, such as diuretics, corticosteroids, and insulin. 4. Use medications that lower uric acid levels; drugs that increase uric acid excretion mainly include probenecid and sulfinpyrazone, and drugs that inhibit uric acid synthesis mainly include febuxostat and allopurinol. However, the treatment with these drugs has specific indications, contraindications, and related side effects. It is advised to use medication under the guidance of a doctor and avoid choosing drugs for treatment arbitrarily.

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Written by Lin Xiang Dong
Endocrinology
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Hyperuricemia Typing

Hyperuricemia can usually be divided into two types: primary hyperuricemia and secondary hyperuricemia. The first type, primary hyperuricemia, is mainly due to congenital purine metabolic disorders, leading to excessive production of uric acid in the body, which then causes hyperuricemia. Secondary hyperuricemia is caused by a variety of acute and chronic diseases, such as common chronic renal failure, and hematological tumors, among others.

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Written by Liang Yin
Endocrinology
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How to reduce high uric acid in hyperuricemia?

The treatment of hyperuricemia includes lifestyle intervention and medication. Lifestyle intervention involves controlling the total caloric intake of the diet, limiting the intake of high-purine foods, avoiding animal offal, shellfish, hot pots, and not consuming tofu, bean sprouts, and other soy products. Smoking and drinking alcohol should be prohibited. It is advocated to eat alkaline foods and choose melon-type vegetables. Appropriate exercise, such as brisk walking, jogging, and aerobic dancing, should be performed. Weight control is necessary, and obese patients should lose weight. Secondly, medication should be used to lower uric acid levels. Options include drugs that promote the excretion of uric acid and drugs that inhibit the production of uric acid, while also alkalizing the urine.

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Written by Li Jing
Rheumatology
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What should be noted for hyperuricemia?

Firstly, hyperuricemia is just found during routine physical examinations or blood tests, showing an increase in blood uric acid levels without the occurrence of gout attacks, meaning there are no symptoms of joint pain. At this time, there is no need for special medication, which means uric acid-lowering drugs are not required. However, you need to be cautious and change your lifestyle habits. For example, abstaining from alcohol, controlling the intake of animal organs, seafood, and barbecued foods. Additionally, drinking more water is necessary, and for overweight individuals, controlling weight and losing weight are important considerations. Also, you should avoid intense physical activities as they can trigger gout attacks, but this doesn't mean no exercise at all; slow walking and swimming are fine.

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Written by Li Jing
Rheumatology
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Are hyperuricemia and high uric acid the same thing?

Firstly, hyperuricemia and high uric acid levels refer to the same concept, defined as blood uric acid levels greater than 420. This condition is described as asymptomatic hyperuricemia, which does not require special treatment at this stage, but it does necessitate changes in lifestyle habits such as abstaining from alcohol, avoiding eating animal organs, seafood, and high-protein foods, not drinking carbonated beverages, and losing weight if obese, to help control body weight. After changing these lifestyle habits, a recheck of the uric acid levels should be done in two weeks to see if there has been a decrease. If the levels have not decreased at that time, sodium bicarbonate tablets can be used to alkalinize the urine. Additionally, increasing water intake to promote the excretion of uric acid and monitoring the dynamic changes in uric acid levels are needed. Once joint pain occurs, which indicates an acute gout attack, proper uric acid-lowering medication is required. (Please undergo medication under the guidance of a professional physician, and do not self-medicate blindly.)

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Written by Luo Juan
Endocrinology
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Can people with hyperuricemia eat wood ear mushrooms?

People with hyperuricemia can eat wood ear mushrooms. As wood ear mushrooms are considered a low-purine food, containing approximately 8.8mg of purines per 100 grams, they can be consumed during hyperuricemia. For hyperuricemia, it is necessary to restrict some high-purine foods, such as animal offal, clams, crabs, oysters, and sardines. Some meats, seafood, peas, and spinach, which also contain a certain amount of purines, can be consumed in moderation. Wood ear mushrooms are a low-purine food and are generally not restricted. Thus, people with hyperuricemia can eat wood ear mushrooms.