What is contraindicated for hyperuricemia?

Written by Chen Xie
Endocrinology
Updated on September 03, 2024
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Hyperuricemia contraindications include the following points: 1. Strictly limit the intake of purines, restrict foods that contain more purines, including animal organs, bone marrow, seafood, fermented foods, beans, etc. 2. Reduce the intake of fats, as fats can decrease the excretion of uric acid. 3. Avoid high-protein foods, such as lean meat, chicken, and duck, which should be boiled and the broth discarded before consumption to avoid eating stewed or marinated meats. 4. Abstain from alcohol, as alcohol can lead to the accumulation of lactate in the body and inhibit the excretion of uric acid, easily triggering gout attacks. 5. Avoid hot pot, as the main ingredients in hot pot are animal organs, shrimp, shellfish, and seafood, and drinking beer with it can aggravate the condition, making these items contraindications for hyperuricemia.

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Written by Li Hui Zhi
Endocrinology
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What are the harms of hyperuricemia?

The dangers of hyperuricemia: Firstly, some individuals might experience gouty arthritis, characterized by localized joint swelling, redness, heat, and pain, affecting mobility. Secondly, prolonged hyperuricemia can damage the kidneys, leading to chronic renal failure. Thirdly, if hyperuricemia persists long-term, it may result in the formation of tophi. Tophi deposited in joints can cause joint deformities and limited mobility. Additionally, hyperuricemia is an independent risk factor for cardiovascular and cerebrovascular diseases, and thus should be taken seriously.

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Written by Liang Yin
Endocrinology
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How to reduce high uric acid in hyperuricemia?

The treatment of hyperuricemia includes lifestyle intervention and medication. Lifestyle intervention involves controlling the total caloric intake of the diet, limiting the intake of high-purine foods, avoiding animal offal, shellfish, hot pots, and not consuming tofu, bean sprouts, and other soy products. Smoking and drinking alcohol should be prohibited. It is advocated to eat alkaline foods and choose melon-type vegetables. Appropriate exercise, such as brisk walking, jogging, and aerobic dancing, should be performed. Weight control is necessary, and obese patients should lose weight. Secondly, medication should be used to lower uric acid levels. Options include drugs that promote the excretion of uric acid and drugs that inhibit the production of uric acid, while also alkalizing the urine.

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Written by Luo Juan
Endocrinology
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The causes of hyperuricemia

The causes of hyperuricemia can currently be divided into two categories: primary and secondary. The cause of most primary hyperuricemia is not yet clear. A few cases are due to enzyme deficiencies, which are related to either excessive production or reduced excretion of uric acid. There is also idiopathic hyperuricemia, such as familial kidney diseases that are associated with hyperuricemia, among others. Some secondary hyperuricemias, for example, are secondary to some congenital metabolic diseases, such as glycogen storage disease. It can also be due to certain systemic diseases, such as leukemia, multiple myeloma, lymphoma, polycythemia vera, hemolytic anemia, etc. Some cases are physiological increases, such as the intake of foods rich in purines, long-term eating and fasting states can also cause increased blood uric acid. Some medications can also lead to hyperuricemia, such as thiazide diuretics, furosemide, ethanol, immunosuppressants, aspirin, etc., which can also cause hyperuricemia. Therefore, the causes of hyperuricemia are diverse, and some causes are still unclear.

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Written by Li Hui Zhi
Endocrinology
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What are the harms of hyperuricemia?

What are the dangers of hyperuricemia? First, it primarily causes gouty arthritis, characterized by redness, swelling, heat, and pain in certain joints, along with limited movement. For some people, the pain can be extremely unbearable. Second, long-term high levels of uric acid can damage the kidneys, leading to impaired kidney function. Third, these purines deposit in the joints forming gout stones, further affecting the function of these joints and reducing the quality of life. Therefore, it is important to treat hyperuricemia early to prevent complications.

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Written by Li Hui Zhi
Endocrinology
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Is hyperuricemia dangerous?

Hyperuricemia is generally diagnosed when the blood uric acid level in males exceeds 420 micromoles per liter and in females exceeds 360 micromoles per liter. Some patients with hyperuricemia are asymptomatic, but others may develop gouty arthritis, characterized by local joint redness, swelling, heat, and pain, and even limited mobility. Some patients may develop gouty nephropathy, leading to abnormal kidney function. There are also instances of patients developing tophi, which can cause joint deformity and even limited mobility. Therefore, if hyperuricemia is not controlled promptly, it poses certain risks and may lead to complications such as tophi, gouty arthritis, and gouty nephropathy.