Causes of Glioma

Written by Chen Yu Fei

Neurosurgery

Updated on September 18, 2024

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Currently, there is no consensus on the specific causes of brain gliomas. Most scholars believe they result from a combination of congenital genetic factors and acquired factors.

In the case of congenital factors, by tracing the medical history of patients with gliomas, it can be found that there is a tendency for a higher concentration of glioma cases among family members.

Acquired factors are mostly seen in severe cranial trauma, extensive gliocyte proliferation, or due to unhealthy lifestyle habits, exposure to carcinogenic chemicals, or long-term damage from highly polluted radiation, which may easily trigger the development of gliomas.

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Written by Chen Yu Fei

Neurosurgery

41sec

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What are the symptoms of glioma?

Patients with gliomas often exhibit a range of symptoms including significant headaches, dizziness, nausea, and vomiting. As the tumor grows, it typically leads to an evident increase in intracranial pressure. Besides the original symptoms, some patients may also experience marked declines in vision, visual field deficits, and papilledema. The growth of the tumor inevitably compresses surrounding tissues, nerves, and blood vessels, leading to a variety of symptoms of neurological damage, such as noticeable hemiplegia, aphasia, and even abnormal sensations in one side of the body, characterized by numbness, pain, and a pins-and-needles sensation.

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Written by Chen Yu Fei

Neurosurgery

46sec

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Principles of Treatment for Glioma

For patients with glioma, the primary treatment method is still to surgically remove the tumor, followed by postoperative radiotherapy, chemotherapy, and other related treatments. The main treatment principle is to detect, diagnose, and treat early. During surgery, the tumor should be removed as completely as possible, and it is advisable to receive postoperative radiotherapy and chemotherapy early to effectively consolidate the surgical treatment effects. This helps to kill tumor cells to the greatest extent, slow down the probability and timing of tumor recurrence, and extend the patient's lifespan as much as possible. Therefore, for patients with glioma, it is recommended to choose to seek surgical treatment at well-known, top-tier hospitals locally.

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Written by Jiang Fang Shuai

Neurosurgery

41sec

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Gliomas grow where?

Glioma is a stubborn malignant tumor of the central nervous system that originates from neuroglial cells. Therefore, gliomas can occur anywhere there are neuroglial cells. Clinically, based on the common sites of the tumors, gliomas can be divided into supratentorial gliomas, which are mostly found in the cerebral hemispheres, frontal lobes, temporal lobes, and parietal lobes, and are less common in the occipital lobes. There are also infratentorial gliomas primarily in the cerebellum. Additionally, a few gliomas are found in the brainstem and spinal cord.

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Written by Gao Yi Shen

Neurosurgery

48sec

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Can gliomas be inherited?

Gliomas have a certain hereditary proportion, but this is not an absolute concept. In clinical practice, there is no clear explanation for the pathogenic factors of gliomas, and theories are generally speculative. For instance, one factor is genetic nature, and there is also some familial clustering which supports the idea of a genetic predisposition. However, it is usually easier to identify purely genetic diseases, but gliomas often involve the inheritance of multiple genes, making it difficult to pinpoint the fundamental factors directly. Additionally, other factors include exposure to radiation and engaging in harmful work, such as producing methanol or solvents, etc. These can also cause genetic mutations leading to gliomas, so the issue is not necessarily solely genetic.

home-news-image

Written by Chen Yu Fei

Neurosurgery

39sec

home-news-image

Causes of Glioma

Currently, there is no consensus on the specific causes of brain gliomas. Most scholars believe they result from a combination of congenital genetic factors and acquired factors. In the case of congenital factors, by tracing the medical history of patients with gliomas, it can be found that there is a tendency for a higher concentration of glioma cases among family members. Acquired factors are mostly seen in severe cranial trauma, extensive gliocyte proliferation, or due to unhealthy lifestyle habits, exposure to carcinogenic chemicals, or long-term damage from highly polluted radiation, which may easily trigger the development of gliomas.