Pneumoconiosis in clinical settings is primarily caused by long-term inhalation of mineral dust, leading to a category of diffuse pulmonary diseases. This type of disease is also considered one of the occupational diseases, with patients experiencing varying degrees of cough, expectoration, and shortness of breath, as well as different levels of breathing difficulty due to prolonged inhalation of high concentrations of dust in severe cases. Therefore, clinically, if pneumoconiosis reaches a moderate level, the first step in treatment involves removing the patient from the dusty environment. Subsequently, symptomatic treatment with appropriate medications is administered to the patient. Treatment usually depends on the symptoms presented by the patient. In cases of evident infection, timely anti-infective treatment should be given, along with medications to suppress cough, facilitate expectoration, and relieve asthma, in order to alleviate discomfort. Moreover, if complications are present, timely treatment of these complications should be administered, along with appropriate anti-fibrotic drugs to manage the clinical symptoms caused by pneumoconiosis.