Precursors of respiratory failure

Written by Li Qiang
Intensive Care Unit
Updated on January 27, 2025
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Respiratory failure can be a very acute condition, or it may evolve gradually due to chronic diseases. The basic precursors of respiratory failure generally include hypoxia or hypercapnia. In the early stages of hypoxia, patients may experience excitement or irritability, characterized by rapid breathing and possibly sweating due to the effort of breathing. Symptoms include accelerated breathing and hypoxia; the patient’s lips may also turn blue. If the level of carbon dioxide increases, once past the initial period of excitement and as the hypoxia worsens, the person may become listless. Gradually, their consciousness may become unclear, manifesting as drowsiness or possibly even coma.

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Written by Yuan Qing
Pulmonology
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Can people with respiratory failure exercise?

Whether people with respiratory failure can exercise depends mainly on whether the respiratory failure occurred acutely or chronically. Generally, it is usually advised against exercising during acute respiratory failure, such as severe pulmonary inflammation, drowning, or failure of the nervous system functions. Exercise during this time can worsen the body's oxygen deficit and increase oxygen consumption, potentially exacerbating the symptoms of the disease. However, for chronic respiratory failure, such as chronic obstructive pulmonary disease (COPD) or chronic pulmonary interstitial fibrosis, patients have long been enduring hypoxia or hypercapnia. These individuals can engage in appropriate respiratory rehabilitation exercises, such as respiratory rehabilitation gymnastics and some traditional Chinese medicine practices, which can greatly aid in the recovery from the disease, particularly respiratory failure. The decision primarily depends on the patient’s specific condition and their physical tolerance.

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Written by Wang Ji Zhong
Internal Medicine
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Causes of CO2 retention in respiratory failure

Respiratory failure manifests as hypoxia and the retention of carbon dioxide. The main cause of carbon dioxide retention is pathological changes in the respiratory system, such as chronic obstructive pulmonary disease with respiratory failure, status asthmaticus, pulmonary heart disease, lung cancer, etc. Some neuropathies that cause paralysis of the respiratory muscles can lead to respiratory dysfunction, resulting in the retention of carbon dioxide in the body, affecting normal cellular metabolism, causing disturbances in acid-base balance and nervous system function, and posing life-threatening conditions. The most important pathogenic mechanism causing carbon dioxide retention in these diseases is still inadequate alveolar ventilation.

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Written by Han Shun Li
Pulmonology
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Does respiratory failure spread?

Respiratory failure is a condition characterized by significant decline in respiratory function and is clinically very serious, being a common critical and acute illness. Respiratory failure itself is not contagious, but certain diseases that cause respiratory failure can be contagious. For example, if it is caused by infectious pulmonary tuberculosis, then the tuberculosis can be transmitted, but respiratory failure itself is not contagious.

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Written by Wang Li Bing
Intensive Care Medicine Department
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How to administer oxygen for respiratory failure.

First, we should evaluate whether the patient has type I or type II respiratory failure based on arterial blood gas analysis. Type I respiratory failure is primarily characterized by low oxygen tension, indicating a state of hypoxia, with normal carbon dioxide tension, in which case high-flow oxygen therapy can be administered. In type II respiratory failure, both the oxygen tension is low and the carbon dioxide tension is high. In this case, only low-flow oxygen therapy should be given, or non-invasive ventilation, or endotracheal intubation connected to mechanical ventilation may be employed.

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Written by Li Qiang
Intensive Care Unit
45sec home-news-image

Precursors of respiratory failure

Respiratory failure can be a very acute condition, or it may evolve gradually due to chronic diseases. The basic precursors of respiratory failure generally include hypoxia or hypercapnia. In the early stages of hypoxia, patients may experience excitement or irritability, characterized by rapid breathing and possibly sweating due to the effort of breathing. Symptoms include accelerated breathing and hypoxia; the patient’s lips may also turn blue. If the level of carbon dioxide increases, once past the initial period of excitement and as the hypoxia worsens, the person may become listless. Gradually, their consciousness may become unclear, manifesting as drowsiness or possibly even coma.