How to administer oxygen for respiratory failure

Written by Peng Miao Yun
Internal Medicine
Updated on September 27, 2024
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If patients with respiratory failure undergo oxygen therapy, it is necessary to choose different therapy plans based on the type of respiratory failure. In the case of Type I respiratory failure, there is simply a lack of oxygen. For Type II respiratory failure, there is not only a lack of oxygen but also an accumulation of carbon dioxide. Therefore, for Type I respiratory failure, the oxygen flow can be higher, over five liters per minute, and the patient can continuously receive oxygen without causing significant side effects. However, for Type II respiratory failure, it is essential to control the oxygen flow at a low rate, under three liters per minute, otherwise, it may lead to other complications.

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Pulmonology
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Is respiratory failure serious?

Respiratory failure is a common and critical condition in the respiratory system, and it is very serious. Respiratory failure manifests as a severe decline in respiratory function, often with significant damage to the lungs' ventilation and gas exchange capabilities. Patients often experience severe chest tightness, difficulty breathing, obvious hypoxic cyanosis, and may even present with symptoms such as convulsions and coma, which can be fatal. Treatment usually requires oxygen therapy and often the assistance of a ventilator. Therefore, respiratory failure is considered a very serious condition clinically and requires proactive management to save the patient's life.

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Precursors of respiratory failure

Respiratory failure can be a very acute condition, or it may evolve gradually due to chronic diseases. The basic precursors of respiratory failure generally include hypoxia or hypercapnia. In the early stages of hypoxia, patients may experience excitement or irritability, characterized by rapid breathing and possibly sweating due to the effort of breathing. Symptoms include accelerated breathing and hypoxia; the patient’s lips may also turn blue. If the level of carbon dioxide increases, once past the initial period of excitement and as the hypoxia worsens, the person may become listless. Gradually, their consciousness may become unclear, manifesting as drowsiness or possibly even coma.

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Written by Peng Miao Yun
Internal Medicine
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Respiratory failure is a disease.

Respiratory failure is a condition caused by severe impairment of lung ventilation and gas exchange functions due to various reasons, leading to ineffective gas exchange. This results in hypoxia in the body, accompanied by either retention or non-retention of carbon dioxide, thereby causing a clinical syndrome of physiological and metabolic disorders. The causes of respiratory failure include diseases of the lung tissue, respiratory tract disorders, pulmonary vascular diseases, and cardiovascular and cerebrovascular diseases, among other factors, all of which can lead to respiratory failure.

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Written by Wang Ji Zhong
Internal Medicine
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Causes of respiratory failure

Respiratory failure is a severe breathing difficulty that can lead to hypoxia and carbon dioxide retention. The causes of respiratory failure can be broadly classified into the following categories: First, there are diseases of the lung parenchyma, such as various lung infections, pneumonia, pulmonary edema, lung abscess, and diseases of the lung interstitium. Another type involves obstruction of the airway, including obstruction in the upper respiratory tract, which covers the nose, pharynx, and larynx, as well as obstructions in the lower respiratory tract, which can also lead to respiratory failure. Third, there are diseases involving the peripheral nervous transmission system and the respiratory machinery, such as acute infectious polyradiculoneuritis, poliomyelitis, and some cervical spine injuries. These can severely affect the respiratory center and respiratory nerves, leading to respiratory failure.

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Written by Peng Miao Yun
Internal Medicine
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Principles of oxygen therapy for respiratory failure

Patients with respiratory failure undergoing oxygen therapy should be treated differently depending on the type of respiratory failure. If it is Type I respiratory failure, it is simply hypoxia without accompanying carbon dioxide retention. Our oxygenation principle can provide slightly higher oxygen flow, with an oxygen flow rate exceeding 5 liters per minute. However, if it is Type II respiratory failure, which comes with severe carbon dioxide retention, it requires continuous low-flow oxygenation. This type of respiratory failure is often caused by chronic pulmonary diseases. Because if high-flow oxygen is provided, the peripheral chemoreceptors' response to hypoxia will decrease in the short term, which will exacerbate respiratory suppression, leading to increased carbon dioxide retention and worsening the condition. Therefore, for Type II respiratory failure, low-flow continuous oxygen should be provided, with an oxygen flow rate controlled below 3 liters per minute.