If knee hyperostosis does not cause pain, swelling, restricted movement, or other discomforts, it generally does not require special treatment. If knee hyperostosis leads to symptoms of osteoarthritis, a step-by-step treatment approach can be adopted. First, changing daily lifestyle habits to avoid excessive load and stress on the knee joints is recommended. This includes avoiding activities like climbing stairs and mountains, keeping warm to prevent cold exposure, and using physical therapy for treatment. Second, medication treatment mainly includes non-steroidal anti-inflammatory painkillers, drugs that nourish joint cartilage, and traditional Chinese medicines that promote blood circulation, relax tendons, and relieve pain. Third, if necessary, treatment can involve injections of sodium hyaluronate into the joint cavity. Fourth, for severe cases of knee hyperostosis, treatments such as arthroscopic debridement, periarticular osteotomy, unicompartmental knee replacement, or total knee arthroplasty can be considered.