Bone hyperplasia is generally caused by degenerative changes that form bony structures, leading to localized pain. In severe cases, it can press on important nerves, causing a range of symptoms. Bone hyperplasia is generally a result of aging-related degeneration and is common in the elderly. However, heavy laborers or athletes can also develop localized bone hyperplasia due to repeated strain and injury. For example, football players may experience bone hyperplasia in the ankle and knee joints, while weightlifters may develop it in their lower back. Therefore, the age at which bone hyperplasia occurs varies depending on specific circumstances.