How is pheochromocytoma diagnosed?

Written by Chen Yu Fei
Neurosurgery
Updated on September 13, 2024
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For patients with pheochromocytoma, comprehensive examinations are necessary for diagnosis. For instance, measuring catecholamines and their metabolites in blood or urine can help determine if there is a noticeable increase in catecholamine levels. Furthermore, adrenal CT scans can be used to assess the condition, where in many cases, significant occupying lesions can be detected through adrenal CT scans. In addition, other related tests also hold diagnostic value and significance, such as magnetic resonance imaging, ultrasound, and related nuclear scanning tests, which can assist in qualitative and locational diagnosis.

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Written by Chen Yu Fei
Neurosurgery
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Pheochromocytoma Test Items

For pheochromocytoma, the usual tests include routine blood tests, routine urine tests, and biochemical examinations. Specific tests mainly involve collecting blood and urine catecholamine metabolites to help diagnose the condition. Furthermore, further localization diagnostics are conducted on the patient via abdominal ultrasound, as well as CT or MRI scans, to determine the specific location of the pheochromocytoma growth. Further examinations are conducted in preparation for subsequent surgery, with treatment generally recommended to be surgical. During treatment, antihypertensive drugs are used in conjunction to control blood pressure and maintain stability of the condition.

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Written by Gao Yi Shen
Neurosurgery
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What department does pheochromocytoma see?

Pheochromocytomas generally require a visit to urology for treatment. Initially, they mostly present with symptoms of hypertension, leading many to first visit cardiology. After differential diagnoses have ruled out other causes and confirmed pheochromocytoma, patients must then seek treatment from urology. Pheochromocytomas are generally located in the adrenal glands, hence they require surgical removal by a urologist. It is crucial to strictly control blood pressure during surgery, as fluctuations can be severe and significantly impact the patient's physical and mental health. Therefore, if a pheochromocytoma is detected, it is critical to seek timely medical treatment for a relatively better prognosis.

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Written by Chen Yu Fei
Neurosurgery
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How is pheochromocytoma diagnosed?

For the examination of pheochromocytoma, it is generally recommended to use qualitative or localization diagnostic methods. Qualitative examinations typically involve collecting metabolites of catecholamines from urine and blood to further facilitate a definitive diagnosis. Localization examinations are conducted through abdominal ultrasound, CT, or MRI to further identify the specific growth location of the pheochromocytoma. After a definitive diagnosis through qualitative and localization examinations, surgery is generally recommended to effectively remove the pheochromocytoma. Additionally, antihypertensive medication can be used to help control symptoms.

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Written by Chen Yu Fei
Neurosurgery
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Causes of hypotension in pheochromocytoma

For cases of hypotension occurring in pheochromocytoma, it is most commonly seen after the surgical removal of the tumor. At this point, the concentration of catecholamines in the blood may significantly decrease, leading to a marked reduction in effective circulating blood volume, and thus causing hypotension. This situation is relatively common after surgery for pheochromocytoma. Usually, after surgical treatment and removal of the tumor, it is important to promptly discontinue the use of receptor blockers in patients and to appropriately replenish blood volume to effectively maintain central venous pressure. This approach can generally counteract the reduction in catecholamine levels caused by surgery, which leads to hypotension.

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Written by Chen Yu Fei
Neurosurgery
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Can pheochromocytoma be cured?

Currently, with the continuous advancement of surgical techniques, pheochromocytomas can be treated promptly and effectively, achieving favorable outcomes. Once a pheochromocytoma is diagnosed and accurately localized, it is advisable to promptly proceed with surgical intervention. Removing the tumor surgically usually results in effective treatment outcomes. Before surgery, imaging studies and biochemical tests are used for the qualitative and locational diagnosis. After the nature and location of the tumor are clearly identified, the success rate of the surgery can also be increased. Pre-operative use of adrenergic receptor blockers can effectively manage the condition, leading to a reduction in blood pressure and lessening the load on the heart, thereby ensuring smooth conduct of the surgery.