Pheochromocytoma Test Items

Written by Chen Yu Fei
Neurosurgery
Updated on September 17, 2024
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For pheochromocytoma, the usual tests include routine blood tests, routine urine tests, and biochemical examinations. Specific tests mainly involve collecting blood and urine catecholamine metabolites to help diagnose the condition. Furthermore, further localization diagnostics are conducted on the patient via abdominal ultrasound, as well as CT or MRI scans, to determine the specific location of the pheochromocytoma growth. Further examinations are conducted in preparation for subsequent surgery, with treatment generally recommended to be surgical. During treatment, antihypertensive drugs are used in conjunction to control blood pressure and maintain stability of the condition.

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Written by Chen Yu Fei
Neurosurgery
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Pheochromocytoma typical manifestations

For pheochromocytoma, the term usually refers to tumors arising from the chromaffin tissue of the neural crest. Clinically, the main typical symptoms include severe hypertension, along with nausea, vomiting, intense headache, and dizziness. Additionally, it may also cause the patient to be in a continuous high metabolic state, characterized by persistent hyperglycemia, nausea, vomiting, and excessive sweating. If not treated promptly and effectively, it may pose serious threats to the patient's heart, brain, and kidneys. In severe cases, it could even be life-threatening. Surgery is commonly recommended for treatment.

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Written by Chen Yu Fei
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Is surgery necessary for pheochromocytoma?

For patients diagnosed with pheochromocytoma, it is recommended to undergo surgery as soon as possible. Complete surgical removal of the tumor often results in a very good therapeutic effect. Before surgery, some medications can be appropriately used for treatment. For example, it is advised to choose adrenergic receptor blockers, which can significantly improve the patient's condition. These can be taken orally before the operation to help gradually regulate blood pressure, or other medications such as calcium channel blockers, angiotensin-converting enzyme inhibitors, and vasodilators may be used. Only through a combination of medication and surgery can satisfactory treatment results be achieved.

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Written by Chen Yu Fei
Neurosurgery
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What medication is used for pheochromocytoma?

For patients with pheochromocytoma, it is advisable to choose antihypertensive drugs during medication. Clinically, there are many types of antihypertensive drugs used to treat pheochromocytoma patients, such as alpha-adrenergic receptor blockers, beta-adrenergic receptor blockers, calcium channel blockers, angiotensin-converting enzyme inhibitors, vasodilators, catecholamine synthesis inhibitors, etc. These drugs can achieve desirable therapeutic effects. Of course, the main treatment for pheochromocytoma is through surgical methods. Only by effectively removing the tumor through surgery can a satisfactory therapeutic effect be achieved, fundamentally leading to a complete cure. (Please use medication under the guidance of a doctor.)

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Written by Chen Yu Fei
Neurosurgery
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Causes of hypotension in pheochromocytoma

For cases of hypotension occurring in pheochromocytoma, it is most commonly seen after the surgical removal of the tumor. At this point, the concentration of catecholamines in the blood may significantly decrease, leading to a marked reduction in effective circulating blood volume, and thus causing hypotension. This situation is relatively common after surgery for pheochromocytoma. Usually, after surgical treatment and removal of the tumor, it is important to promptly discontinue the use of receptor blockers in patients and to appropriately replenish blood volume to effectively maintain central venous pressure. This approach can generally counteract the reduction in catecholamine levels caused by surgery, which leads to hypotension.

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Written by Gan Jun
Endocrinology
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Is it okay not to remove a pheochromocytoma?

For patients diagnosed with pheochromocytoma, it is recommended that surgical removal is the best option. Pheochromocytoma, also known as an adrenal medullary tumor, originates from the sympathetic ganglia in the adrenal medulla and other related chromaffin tissues. This type of disease can secrete large amounts of catecholamines, causing episodic or persistent hypertension, as well as other related metabolic disorder syndromes. It often presents as potentially fatal hypertension, accompanied by potentially fatal hypotension or even shock, leading to symptoms such as increased heart rate, palpitations, and fear. Patients with pheochromocytoma are advised to undergo timely surgical treatment, as general drug treatments are unable to control or cure the condition.