How is a pituitary tumor caused?

Written by Chen Yu Fei
Neurosurgery
Updated on March 18, 2025
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At present, there is no definitive conclusion on how pituitary tumors are formed and further developed. Clinically, it is mostly believed to be the result of a combination of congenital genetic factors and adverse environmental factors acquired later in life. For patients with pituitary tumors, they are often seen in some special familial genetic diseases. In the family medical history, a tendency for a higher accumulation of family members can be observed. Additionally, some pituitary tumor patients are also found in clear familial genetic endocrine diseases. Moreover, patients who are overworked, fatigued, under stress, and experience endocrine hormone disorders are also affected. Exposure to radioactive contamination and chemical carcinogens can also potentially lead to pituitary tumors.

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Written by Gao Yi Shen
Neurosurgery
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How much does a pituitary tumor grow in a year?

At present, in clinical practice, there is no evidence to show how much a pituitary tumor can grow in a year, because the specific pathological nature of pituitary tumors varies, the overall health status of an individual differs, as well as whether a corresponding disease mechanism has developed, and whether regular treatment has been administered. These factors definitely influence the pituitary tumor. For some benign or non-functioning pituitary tumors, the growth is very slow after certain treatments, and they will not recur or grow after surgical intervention. However, sometimes, malignant pituitary tumors can grow very quickly within a year, significantly affecting the surrounding nerve tissues due to compression. Therefore, it is crucial to have regular follow-ups or seek early treatment if a pituitary tumor is present, as this is the best approach to treatment.

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Written by Chen Yu Fei
Neurosurgery
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Can pituitary tumors be cured?

Currently, for the treatment of pituitary tumors, it is generally recommended in clinical practice to opt for a complete resection via a transnasal-transsphenoidal approach. Most patients can achieve good therapeutic outcomes through surgery. The main goals of surgically treating pituitary tumors are to remove the tumor, decompress the visual pathways, and help restore and maintain the function of the pituitary and other neurological functions. Most patients can achieve good therapeutic results after treatment. Additionally, after receiving treatment, patients' original symptoms gradually alleviate or even disappear, and no longer worsen. Therefore, from this perspective, it is recommended that all symptomatic pituitary tumor patients should timely seek medical consultation at local hospitals and receive early treatment.

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Written by Chen Yu Fei
Neurosurgery
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What is a pituitary tumor?

Pituitary tumors refer to a type of benign tumor that occurs at the site of the pituitary fossa. Generally, they grow relatively slowly. In the early stages of the disease, there are usually no obvious symptoms or signs. Some patients may occasionally feel mild headaches or dizziness, which most can tolerate. As the size of the pituitary tumor gradually increases, it often affects the surrounding critical tissues, nerves, and organs, primarily impacting pituitary function, thereby leading to pituitary hypofunction. This affects the secretion of endocrine hormones in the body, causing abnormal secretion of endocrine hormones, and resulting in a series of symptoms and signs. For example, male patients may experience abnormalities in the secretion of male hormones, leading to difficulties with erection, while female patients are likely to experience menstrual disorders and irregular menstruation.

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Written by Chen Yu Fei
Neurosurgery
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Can pituitary tumors heal on their own?

Under normal circumstances, pituitary tumors generally do not heal spontaneously. Pituitary tumors are benign tumors and although they grow slowly, they tend to continue growing. When they enlarge to a certain extent, they produce a series of symptoms and signs, such as headaches behind the eye sockets, the forehead, and both temporal sides. If the tumor breaks through the sellar diaphragm, it might also affect the optic nerve, leading to decreased vision and visual field defects. Moreover, it can severely erode the pituitary gland, causing symptoms and signs like decreased pituitary function, endocrine hormone disorders, and bringing significant suffering to the patient.

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Written by Chen Yu Fei
Neurosurgery
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Is a pituitary tumor serious?

Pituitary tumors are mostly benign. The tumors grow slowly, but due to their special location adjacent to the pituitary gland, when the size of the pituitary tumor increases to a certain extent, it will inevitably affect the pituitary, impairing its function and leading to pituitary dysfunction. This dysfunction manifests as endocrine hormonal imbalances, resulting in a series of symptoms and signs. Therefore, it is usually recommended to treat pituitary tumors surgically. Clinically, it is generally advised to choose the transnasal transsphenoidal approach for complete resection of the pituitary tumor.