Pituitary tumor complications

Written by Chen Yu Fei
Neurosurgery
Updated on May 04, 2025
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For patients with pituitary tumors, it is common to see certain complications, especially post-surgery, such as hematoma in the sellar region, life-threatening nasal hemorrhage, pseudoaneurysm rupture bleeding, cerebrospinal fluid rhinorrhea, meningitis, reduced pituitary function, diabetes insipidus, as well as associated issues with fluid, electrolyte imbalance, and acid-base imbalance. Some patients may also experience rare complications like eye muscle paralysis and nasal septum perforation. Therefore, for patients with pituitary tumors, it is crucial to closely monitor any changes in their condition after surgery. If any abnormalities are found, a prompt re-examination with a head CT should be conducted to observe changes and provide appropriate treatment.

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Written by Chen Yu Fei
Neurosurgery
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The difference between pituitary tumors and pituitary adenomas

The difference between a pituitary tumor and a pituitary adenoma mainly lies in the extent of the affected tissue involved. Generally, pituitary tumors may have a broader range than pituitary adenomas, meaning that pituitary tumors include pituitary adenomas. Normally, a pituitary adenoma specifically refers to tumors occurring in the anterior lobe of the pituitary gland, as this lobe primarily consists of glandular tissue. Meanwhile, the posterior lobe of the pituitary is mainly neurohypophysis. Therefore, tumors typically referred to as pituitary adenomas occur in the anterior lobe. If a tumor is in the posterior lobe, it cannot be called a pituitary adenoma, but it still falls under the category of pituitary tumors.

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Neurosurgery
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Pituitary tumors are located in the pituitary gland.

Pituitary tumors are benign tumors that grow slowly, mostly within the pituitary fossa. Due to their proximity to the pituitary gland, small pituitary tumors generally do not show obvious symptoms. However, as the tumor size increases, it can easily compress the pituitary gland, affecting its function, resulting in pituitary dysfunction and causing an endocrine hormone disorder. This leads to a variety of symptoms and signs in patients. A cranial CT or MRI, including an enhanced MRI scan of the pituitary, can reveal a high-density shadow in the pituitary fossa, indicating the presence of an intracranial mass.

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Written by Chen Yu Fei
Neurosurgery
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Is a pituitary tumor easy to treat?

Our current understanding of pituitary tumors is quite deep, and we have accumulated rich treatment experience in the pathogenesis, disease progression, and treatment of pituitary tumors. Therefore, it is recommended to use surgical methods for pituitary tumor patients, especially those with obvious symptoms. Clinically, it is generally recommended to choose the transnasal-transsphenoidal approach for a complete resection of the pituitary tumor. For most patients, this can achieve good therapeutic effects. Moreover, with the continuous advancement of diagnostic techniques, early detection and treatment of small early pituitary microadenomas through complete surgical resection can also achieve good therapeutic outcomes.

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Written by Chen Yu Fei
Neurosurgery
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Are pituitary tumors prone to recurrence?

Pituitary tumors in the brain are benign tumors that grow slowly. When the tumor size is relatively small, there are generally no clear symptoms or signs, and most patients can work, live, and study like normal people. It is recommended to treat pituitary tumors with surgical methods. Most pituitary tumors are benign. If they can be completely removed through microscopic surgery, or through the transnasal transsphenoidal approach, minimally invasive surgery can achieve ideal treatment results and generally will not recur. However, for individual patients with pituitary tumors, if the tumor is malignant, it may easily adhere to surrounding tissues in the early stages, making it difficult to completely remove surgically, thus it is prone to recurrence.

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Written by Chen Yu Fei
Neurosurgery
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Is pituitary tumor surgery done under general anesthesia?

For patients with pituitary tumors, general anesthesia is typically recommended for surgery. Clinically, a combined inhalational and intravenous anesthesia approach is adopted for treatment. Before surgery, anesthesia induction is carried out to stabilize the patient, who then undergoes tracheal intubation for general combined anesthesia. As the surgery nears completion, appropriate medication may be used to help shorten the anesthesia process. After the surgery is fully completed, the patient is transferred to the recovery room. Once the anesthetic drugs are gradually metabolized and consciousness returns to clarity, the tracheal tube is effectively removed.