Pituitary tumor complications

Written by Chen Yu Fei
Neurosurgery
Updated on May 04, 2025
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For patients with pituitary tumors, it is common to see certain complications, especially post-surgery, such as hematoma in the sellar region, life-threatening nasal hemorrhage, pseudoaneurysm rupture bleeding, cerebrospinal fluid rhinorrhea, meningitis, reduced pituitary function, diabetes insipidus, as well as associated issues with fluid, electrolyte imbalance, and acid-base imbalance. Some patients may also experience rare complications like eye muscle paralysis and nasal septum perforation. Therefore, for patients with pituitary tumors, it is crucial to closely monitor any changes in their condition after surgery. If any abnormalities are found, a prompt re-examination with a head CT should be conducted to observe changes and provide appropriate treatment.

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Written by Chen Yu Fei
Neurosurgery
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Pituitary tumor examination items

For patients with pituitary tumors, it is first recommended to perform a cranial CT or MRI examination, and if necessary, a cranial MRI with contrast and a pituitary MRI with contrast can be done to help determine the specific location, size, and relationship of the pituitary tumor with surrounding important blood vessels and nerves. Additionally, blood tests are needed to examine the levels of endocrine hormones in the body, including cortisol, growth hormone, prolactin, thyroid hormones, and other related hormone levels. Furthermore, further examinations of the patient's cardiopulmonary function, such as electrocardiograms, echocardiograms, and chest CT scans, are also required.

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What should I do about a pituitary tumor?

When a pituitary tumor occurs, we generally recommend surgery as the treatment method. Of course, specific analysis should be done based on the individual circumstances of the patient before surgery. In cases where the tumor is small and there are no obvious clinical symptoms—discovered incidentally during other related examinations—such patients can temporarily take medication and should be closely monitored with regular follow-ups to observe any changes in their condition. However, for patients who have clear clinical symptoms and display endocrine hormone imbalances, such as men experiencing significant erectile dysfunction and women having menstrual disorders, surgery is generally recommended as the treatment method.

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The difference between pituitary tumors and pituitary adenomas

The difference between a pituitary tumor and a pituitary adenoma mainly lies in the extent of the affected tissue involved. Generally, pituitary tumors may have a broader range than pituitary adenomas, meaning that pituitary tumors include pituitary adenomas. Normally, a pituitary adenoma specifically refers to tumors occurring in the anterior lobe of the pituitary gland, as this lobe primarily consists of glandular tissue. Meanwhile, the posterior lobe of the pituitary is mainly neurohypophysis. Therefore, tumors typically referred to as pituitary adenomas occur in the anterior lobe. If a tumor is in the posterior lobe, it cannot be called a pituitary adenoma, but it still falls under the category of pituitary tumors.

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How many days of hospitalization for pituitary tumor surgery?

For patients with pituitary tumors, it normally takes about one to two weeks to undergo surgery and be hospitalized. After surgery, it is appropriate for patients to rest in bed and refrain from getting up too early, mainly to monitor for any occurrence of cerebrospinal fluid rhinorrhea. Premature activity might lead to cerebrospinal fluid rhinorrhea or even trigger intracranial infections. Additionally, after surgery, it is important to perform blood tests to check the levels of endocrine hormones in the body, primarily to assess whether important electrolyte and hormone levels are normal. If there are abnormalities, adjustments should be made promptly, and discharge can be considered once the patient's condition is stable.

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Written by Chen Yu Fei
Neurosurgery
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Is a 2cm pituitary tumor big?

In the case of pituitary tumors, if the size reaches two centimeters, it is relatively large. Under normal circumstances, pituitary tumors can be classified into several types based on their size: microadenomas are generally smaller than one centimeter, macroadenomas are larger than 1.0 centimeter, and giant adenomas are larger than 3.0 centimeters. Usually, a two-centimeter pituitary tumor is already considered a macroadenoma. Normally, such large pituitary tumors often compress the surrounding pituitary tissue, causing hypofunction of the pituitary tissue and significant hormonal disturbances, which can lead to a range of uncomfortable symptoms and signs in patients.