What should I do about a pituitary tumor?

Written by Chen Yu Fei
Neurosurgery
Updated on September 05, 2024
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When a pituitary tumor occurs, we generally recommend surgery as the treatment method. Of course, specific analysis should be done based on the individual circumstances of the patient before surgery. In cases where the tumor is small and there are no obvious clinical symptoms—discovered incidentally during other related examinations—such patients can temporarily take medication and should be closely monitored with regular follow-ups to observe any changes in their condition. However, for patients who have clear clinical symptoms and display endocrine hormone imbalances, such as men experiencing significant erectile dysfunction and women having menstrual disorders, surgery is generally recommended as the treatment method.

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Written by Chen Yu Fei
Neurosurgery
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Pituitary tumors are located in the pituitary gland.

Pituitary tumors are benign tumors that grow slowly, mostly within the pituitary fossa. Due to their proximity to the pituitary gland, small pituitary tumors generally do not show obvious symptoms. However, as the tumor size increases, it can easily compress the pituitary gland, affecting its function, resulting in pituitary dysfunction and causing an endocrine hormone disorder. This leads to a variety of symptoms and signs in patients. A cranial CT or MRI, including an enhanced MRI scan of the pituitary, can reveal a high-density shadow in the pituitary fossa, indicating the presence of an intracranial mass.

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Written by Chen Yu Fei
Neurosurgery
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Is a 2cm pituitary tumor big?

In the case of pituitary tumors, if the size reaches two centimeters, it is relatively large. Under normal circumstances, pituitary tumors can be classified into several types based on their size: microadenomas are generally smaller than one centimeter, macroadenomas are larger than 1.0 centimeter, and giant adenomas are larger than 3.0 centimeters. Usually, a two-centimeter pituitary tumor is already considered a macroadenoma. Normally, such large pituitary tumors often compress the surrounding pituitary tissue, causing hypofunction of the pituitary tissue and significant hormonal disturbances, which can lead to a range of uncomfortable symptoms and signs in patients.

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Written by Chen Yu Fei
Neurosurgery
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What is a pituitary tumor?

Pituitary tumors refer to a type of benign tumor that occurs at the site of the pituitary fossa. Generally, they grow relatively slowly. In the early stages of the disease, there are usually no obvious symptoms or signs. Some patients may occasionally feel mild headaches or dizziness, which most can tolerate. As the size of the pituitary tumor gradually increases, it often affects the surrounding critical tissues, nerves, and organs, primarily impacting pituitary function, thereby leading to pituitary hypofunction. This affects the secretion of endocrine hormones in the body, causing abnormal secretion of endocrine hormones, and resulting in a series of symptoms and signs. For example, male patients may experience abnormalities in the secretion of male hormones, leading to difficulties with erection, while female patients are likely to experience menstrual disorders and irregular menstruation.

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Written by Chen Yu Fei
Neurosurgery
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How to treat pituitary tumors?

Currently, the treatment of pituitary tumors can generally be conducted through various methods such as surgery, medication, and radiation therapy. The specific choice of treatment for a patient depends on the patient's individual circumstances, including factors such as gender, age, the current size of the pituitary tumor, whether there is damage to other vital organs, and the patient's overall condition. For most symptomatic patients, surgery is usually recommended. Clinically, it is generally recommended to choose transnasal transsphenoidal surgery for complete removal, which often achieves very good therapeutic effects. However, for some pituitary tumors located in special positions where complete surgical removal is not achievable, radiation therapy or Gamma Knife surgery can be used in conjunction.

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Written by Chen Yu Fei
Neurosurgery
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Pituitary tumor examination items

For patients with pituitary tumors, it is first recommended to perform a cranial CT or MRI examination, and if necessary, a cranial MRI with contrast and a pituitary MRI with contrast can be done to help determine the specific location, size, and relationship of the pituitary tumor with surrounding important blood vessels and nerves. Additionally, blood tests are needed to examine the levels of endocrine hormones in the body, including cortisol, growth hormone, prolactin, thyroid hormones, and other related hormone levels. Furthermore, further examinations of the patient's cardiopulmonary function, such as electrocardiograms, echocardiograms, and chest CT scans, are also required.