Is the ESR high in Hashimoto's thyroiditis?

Written by Chen Xie
Endocrinology
Updated on September 02, 2024
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Hashimoto's thyroiditis belongs to autoimmune thyroiditis, which is caused by the presence of autoantibodies that destroy the thyroid follicular cells, leading to the failure of thyroid cells. For patients with Hashimoto's thyroiditis, the erythrocyte sedimentation rate (ESR) generally does not increase. However, if a patient experiences neck discomfort or sore throat, and the ESR increases, even accompanied by fever, it is necessary to rule out whether subacute thyroiditis is present. If the patient has subacute thyroiditis, it indicates that a viral infection has caused the destruction of the thyroid cells, which might increase the ESR.

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Written by Chen Xie
Endocrinology
47sec home-news-image

Does Hashimoto's thyroiditis cause weight loss?

Hashimoto's thyroiditis is an autoimmune thyroiditis where autoantibodies within the body cause the destruction of thyroid follicular cells, leading to thyroid cell failure. During the course of Hashimoto's thyroiditis, hyperthyroidism may occur. Due to the destruction of thyroid follicles by autoantibodies, a significant release of thyroid hormones into the blood occurs, resulting in a hyperthyroid state. Therefore, symptoms such as weight loss, heat intolerance, and excessive sweating which are typical of hyperthyroidism may also appear in Hashimoto's thyroiditis. However, as the disease progresses, the condition gradually leads to decreased thyroid function.

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Written by Tang Zhuo
Endocrinology
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What to do with Hashimoto's thyroiditis?

Hashimoto's thyroiditis is the most common clinical type of thyroiditis, with over 90% occurring in females. It is also the major cause of primary hypothyroidism. The onset of Hashimoto's thyroiditis is insidious and progresses slowly. Early clinical manifestations are often atypical. Therefore, the treatment of Hashimoto's thyroiditis should be tailored to different circumstances. If a patient with Hashimoto's thyroiditis has normal thyroid function, then no special treatment is needed, only regular follow-up is required. If the patient develops hypothyroidism, thyroid hormone replacement therapy should be administered using either thyroxine tablets or levothyroxine tablets until the maintenance dose is reached, to improve clinical symptoms and normalize thyroid function. Another category includes patients with Hashimoto's hyperthyroidism, who generally do not require treatment as they may go through phases of hyperthyroidism, normal thyroid function, and hypothyroidism. Transient hyperthyroidism can be managed symptomatically with β-blockers. For cases highly suspected of concurrent Hashimoto's thyroiditis with thyroid cancer or lymphoma, surgical treatment can be considered.

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Written by Xu Dong Dong
Endocrinology
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Can Hashimoto's thyroiditis breastfeed?

Patients with Hashimoto's thyroiditis can breastfeed. It is important for those in a hyperthyroid phase, especially when taking anti-thyroid medications, to switch to breastfeeding-safe medications beforehand and to regularly monitor thyroid function to ensure it remains within normal limits. Patients in a hypothyroid phase should also regularly monitor their thyroid function and adjust their replacement medication dosage accordingly. Newborns should have their thyroid function and related antibodies regularly tested from birth onwards. (Please medicate under the guidance of a physician.)

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Written by Chen Xie
Endocrinology
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Is Hashimoto's thyroiditis hereditary?

Hashimoto's thyroiditis is an autoimmune thyroid disease and is not hereditary. However, it tends to cluster in families, meaning if one's parents have a history of Hashimoto's thyroiditis, their offspring have a relatively higher risk of developing the disease. However, this is not absolute heredity; it simply indicates a familial clustering tendency. Treatment for Hashimoto's thyroiditis is relatively effective. If hypothyroidism occurs, one only needs to take lifelong replacement therapy with levothyroxine to maintain thyroid function within the normal range, which has minimal impact on the body. Therefore, there is no need for excessive worry.

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Written by Li Hui Zhi
Endocrinology
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How is Hashimoto's thyroiditis diagnosed?

Firstly, it is important to check thyroid function for Hashimoto's thyroiditis, which involves a specific antibody, the anti-thyroid peroxidase antibody (TPOAb). If this antibody is significantly elevated, it supports the diagnosis of Hashimoto's thyroiditis. Additionally, a thyroid ultrasound should be combined, and if there is severe enlargement, a thyroid fine-needle aspiration can be conducted to assist in treatment. After a confirmed diagnosis of Hashimoto's thyroiditis, it is also necessary to assess thyroid function to determine if there is concurrent hyperthyroidism or hypothyroidism. Treatment should then be administered based on the specific condition of the patient.