Is the ESR high in Hashimoto's thyroiditis?

Written by Chen Xie
Endocrinology
Updated on September 02, 2024
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Hashimoto's thyroiditis belongs to autoimmune thyroiditis, which is caused by the presence of autoantibodies that destroy the thyroid follicular cells, leading to the failure of thyroid cells. For patients with Hashimoto's thyroiditis, the erythrocyte sedimentation rate (ESR) generally does not increase. However, if a patient experiences neck discomfort or sore throat, and the ESR increases, even accompanied by fever, it is necessary to rule out whether subacute thyroiditis is present. If the patient has subacute thyroiditis, it indicates that a viral infection has caused the destruction of the thyroid cells, which might increase the ESR.

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Written by Chen Li Ping
Endocrinology
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Does Hashimoto's thyroiditis hurt?

Hashimoto's thyroiditis is a chronic lymphocytic thyroiditis. The typical manifestation of Hashimoto's thyroiditis is chronic diffuse goiter, but the patient is asymptomatic. The patient's thyroid will show diffuse, painless mild to moderate enlargement, firm texture, slight tenderness upon pressure, local compression in the neck, and generally not very pronounced systemic symptoms, often with discomfort in the throat. Thyroid pain or tenderness in Hashimoto's thyroiditis is still quite rare; if pain is present, differentiation from subacute thyroiditis is necessary.

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Written by Chen Xie
Endocrinology
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Does Hashimoto's thyroiditis cause weight loss?

Hashimoto's thyroiditis is an autoimmune thyroiditis where autoantibodies within the body cause the destruction of thyroid follicular cells, leading to thyroid cell failure. During the course of Hashimoto's thyroiditis, hyperthyroidism may occur. Due to the destruction of thyroid follicles by autoantibodies, a significant release of thyroid hormones into the blood occurs, resulting in a hyperthyroid state. Therefore, symptoms such as weight loss, heat intolerance, and excessive sweating which are typical of hyperthyroidism may also appear in Hashimoto's thyroiditis. However, as the disease progresses, the condition gradually leads to decreased thyroid function.

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Written by Chen Xie
Endocrinology
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Is Hashimoto's thyroiditis hereditary?

Hashimoto's thyroiditis is an autoimmune thyroid disease and is not hereditary. However, it tends to cluster in families, meaning if one's parents have a history of Hashimoto's thyroiditis, their offspring have a relatively higher risk of developing the disease. However, this is not absolute heredity; it simply indicates a familial clustering tendency. Treatment for Hashimoto's thyroiditis is relatively effective. If hypothyroidism occurs, one only needs to take lifelong replacement therapy with levothyroxine to maintain thyroid function within the normal range, which has minimal impact on the body. Therefore, there is no need for excessive worry.

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Written by Chen Xie
Endocrinology
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Hashimoto's thyroiditis diagnostic indicators

Hashimoto's thyroiditis is a type of autoimmune thyroiditis, which can present in various phases regarding thyroid function, manifesting as hyperthyroidism, hypothyroidism, or normal thyroid function. Therefore, for patients with Hashimoto's thyroiditis, it is necessary to check thyroid function to understand its status. Since Hashimoto's thyroiditis is an autoimmune thyroiditis, the thyroid peroxidase antibodies and thyroglobulin antibodies are generally elevated. Additionally, it is necessary to perform thyroid ultrasound to assess the thyroid's condition. For some difficult-to-distinguish patients, a further examination such as a 131I uptake test can be conducted, where the uptake rate in Hashimoto's thyroiditis is reduced. Even further, a fine needle aspiration biopsy of the thyroid can be performed, where we can observe significant lymphocyte infiltration.

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Written by Chen Xie
Endocrinology
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Can Hashimoto's thyroiditis be cured?

Hashimoto's thyroiditis is an autoimmune thyroiditis where the body itself has autoantibodies that lead to the destruction of thyroid follicular cells, resulting in the failure of thyroid cells. Therefore, Hashimoto's thyroiditis can manifest as hyperthyroidism, euthyroidism, and hypothyroidism. Ultimately, Hashimoto's thyroiditis may develop into hypothyroidism. Hypothyroidism is proliferative and generally cannot be completely cured, but clinical remission can be achieved through oral administration of levothyroxine. However, Hashimoto's thyroiditis cannot be completely cured and requires lifelong replacement therapy.