Symptoms and early signs of esophageal cancer.

Written by Cui Fang Bo
Oncology
Updated on July 03, 2025
00:00
00:00

The most typical early symptom of esophageal cancer is progressive dysphagia. Progressive dysphagia means that the patient initially has difficulty swallowing solid food, later experiences difficulty swallowing semi-liquid food, and finally may find it difficult to swallow even liquids. Other early symptoms of esophageal cancer include pain behind the sternum and vomiting after eating. For patients who exhibit these symptoms and are suspected of having esophageal cancer, an endoscopic examination should be performed. During the endoscopy, abnormal masses in the esophagus can be detected, and tissue samples can be taken from these masses for histopathological examination. Patients diagnosed with esophageal cancer through pathology are primarily recommended to undergo surgical treatment. Patients who are not suitable for surgery can receive comprehensive treatment such as radiotherapy and chemotherapy.

Other Voices

doctor image
home-news-image
Written by Peng Li Bo
Oncology
1min 2sec home-news-image

Esophageal cancer T3 belongs to which stage?

For the staging of esophageal cancer, it not only depends on the T stage, but also on the N and M stages. If we are just considering the T stage, it is T3. If there are no N0 and M0 stages, it is relatively early and surgery can be considered. However, if looking only at T3 and the N stage involves lymph node involvement (N1, N2, or N3), with regional or distant lymph node metastasis, then the staging of the esophageal cancer is relatively late. Furthermore, if there is an M stage, which indicates the presence of distant organ metastasis, then it is classified as advanced stage. Therefore, the T stage alone for esophageal cancer does not determine whether it is early, intermediate, or late stage. It is necessary to look in conjunction with the N and M stages to determine the overall staging.

doctor image
home-news-image
Written by Liu Liang
Oncology
27sec home-news-image

Esophageal cancer metastasis pathways

"In terms of the metastatic pathways of esophageal cancer, the first one is through the bloodstream, known as hematogenous spread. This primarily results in metastases to distant organs such as the lungs, liver, bones, etc. The second pathway is via the lymphatic system. Lymphatic spread leads to metastases in regional lymph nodes and distant lymph nodes. The third pathway is through local invasion by the tumor, where the esophageal cancer can invade nearby organs and spread. These are the pathways through which metastasis occurs."

doctor image
home-news-image
Written by Zhu Dan Hua
Gastroenterology
1min 6sec home-news-image

Distinction between esophagitis and esophageal cancer

Esophagitis and esophageal cancer are different diseases. Esophagitis refers to inflammatory changes in the esophagus, characterized by mucosal congestion, edema, and even erosion, commonly seen in middle-aged patients. Patients most often seek medical attention for abdominal discomfort or chest pain, and some may also experience nausea, belching, and so on. Esophageal cancer is more common in older patients, primarily presenting with progressively worsening dysphagia, accompanied by nausea, vomiting, and so on. Some cancer symptoms may be similar to those of esophagitis. The main method for differential diagnosis includes a thorough gastroscopic examination to provide further clarification. Esophagitis mainly manifests as inflammatory changes in the esophageal mucosa; in the case of esophageal cancer, a gastroscopic examination can directly reveal esophageal tumors, thereby facilitating differentiation.

doctor image
home-news-image
Written by Peng Li Bo
Oncology
49sec home-news-image

The difference between esophagitis and esophageal cancer

The differences between esophagitis and esophageal cancer are significant. Esophagitis is an inflammation and is benign, but esophageal cancer is malignant, marking a stark contrast between the two. However, both esophagitis and esophageal cancer can have similar clinical symptoms, such as acid reflux, hiccups, heartburn, pain behind the breastbone, discomfort, and a burning sensation behind the breastbone, so symptoms can be similar. However, a more typical symptom of esophageal cancer is a sensation of swallowing obstruction, since there is actually something in the esophagus. Inflammation, after all, is just that, and it does not involve a mass forming inside the esophagus that could block it, hindering the ability to drink water, eat food, or swallow.

doctor image
home-news-image
Written by Peng Li Bo
Oncology
43sec home-news-image

What are the precancerous lesions of esophageal cancer?

The most common precancerous lesion of esophageal cancer is Barret's esophagus, which is formed by the chronic stimulation of the esophageal epithelium by chronic reflux esophagitis. Of course, this includes some chronic esophageal ulcers and long-term leukoplakia of the esophagus. These recurrent esophageal ulcers could potentially transform into atypical hyperplasia and then further into carcinoma in situ. However, the progression from precancerous lesions to actual cancer can take a very long time, possibly many years or even over a decade. Therefore, having a precancerous lesion does not necessarily lead to esophageal cancer.