The difference between gallbladder polyps and gallbladder cancer in ultrasound examinations

Written by Liu Wu Cai
Hepatobiliary Surgery
Updated on September 08, 2024
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For gallbladder polyps, they are a type of benign tumor, so under color ultrasound, benign protrusions can be observed, and there are no adhesions with surrounding tissues, nor is there obvious blood vessel supply. For gallbladder cancer, it is a type of malignant tumor, so at this time, adhesions with surrounding tissues can be observed under color ultrasound, and there is obvious blood vessel supply. Therefore, for patients with gallbladder polyps and gallbladder cancer, their treatment methods are completely different, and attention should be paid. If it is a gallbladder polyp, patients generally do not exhibit obvious symptoms and do not require special management. For gallbladder cancer patients, however, it severely affects their quality of life and lifespan, so attention must be paid, and early surgical removal and treatment must be undertaken to achieve a cure.

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Gallbladder cancer CT manifestations

Gallbladder cancer commonly occurs in females, and its causes may be related to chronic and long-term irritation from cholecystitis and gallstones. On a CT scan, based on the tumor's pathological classification and growth patterns, it can be divided into the following types: The first type is the infiltrative type, which is characterized by irregular thickening of the gallbladder wall, usually greater than 1 cm, with a rough edge, and significant enhancement is seen after contrast enhancement. The second type is the mass-forming type, which presents as a large soft tissue mass filling the gallbladder, also showing significant enhancement after injection of contrast agent. The third type is the nodular type, which presents as either single or multiple nodules that protrude into the gallbladder cavity, appearing papillary or cauliflower-like. The fourth type is the obstructive type, generally a tumor at the neck of the gallbladder, causing obstruction of the common bile duct.

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Hepatobiliary Surgery
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How long does it take for gallstones to develop into gallbladder cancer?

Gallstones do not necessarily develop into gallbladder cancer. For patients with gallstones, they mainly experience discomfort and pain in the upper right abdomen, especially after overeating or drinking alcohol, when the symptoms suddenly appear. Gallstones do not necessarily cause gallbladder cancer. If symptoms occur, surgery should be performed at this time. Only through surgery can a cure for gallbladder cancer be achieved. It is a common malignant tumor of the gallbladder, mainly caused by repeated inflammatory stimuli or genetic factors. At this time, surgery should be performed to better improve the prognosis of the patient. Early stage gallbladder cancer can be completely removed surgically to achieve a cure.

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Hepatobiliary Surgery
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Can gallbladder cancer with liver metastasis be treated?

If a gallbladder cancer patient experiences liver metastasis, aggressive treatment can be applied, but it can only be symptomatic treatment and cannot achieve a cure. Gallbladder cancer is a type of malignancy with a high degree of malignancy, prone to metastasis to other parts, and with very poor treatment outcomes. If liver metastasis occurs, the condition is severe and has reached the middle to late stages. Treatment cannot involve surgical removal at this time. Instead, active management should be employed to improve quality of life and better control the disease, though it cannot be cured. When gallbladder cancer patients experience liver metastasis, symptoms may include pain in the liver area, abnormal liver function, hypoalbuminemia, ascites, and other clinical symptoms. At this time, symptomatic treatment should be actively pursued to better maintain the patient's life and improve quality of life.

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Hepatobiliary Surgery
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Can gallbladder cancer be detected through blood tests?

Blood tests generally cannot detect gallbladder cancer because there are no specific markers in the blood tests for gallbladder cancer. Although some tumor markers may be significantly elevated, they are not specific. Therefore, diagnosis of gallbladder cancer can be refined through abdominal CT, color ultrasound, and if necessary, puncture tissue for pathological examination to confirm the nature. Once diagnosed with gallbladder cancer, surgery should be performed as soon as possible because gallbladder cancer is a highly malignant, rapidly developing, and poor prognosis malignancy. It is important to pay attention to it and handle it promptly to improve the prognosis and potentially extend the patient’s life.

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Difference between early-stage and mid-stage gallbladder cancer

For gallbladder cancer, its staging is mainly based on the size of the tumor and whether there are metastases to other parts of the body, including lymph node metastases. In early-stage gallbladder cancer patients, the tumor is generally small and there are no metastases to other parts of the body. At this stage, patients typically do not show specific symptoms. Additionally, for patients with mid-stage gallbladder cancer, they may experience discomfort or dull pain in the upper right abdomen, and may also experience weight loss, possibly even developing cachexia. Therefore, gallbladder cancer patients can undergo surgical removal and a pathological examination can provide a better assessment of the pathological stage, leading to a better treatment plan.