Does nasopharyngeal carcinoma cause excessive phlegm?

Written by Yan Chun
Oncology
Updated on May 05, 2025
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Patients with nasopharyngeal carcinoma often exhibit clinical manifestations of excessive sputum, which is considered to be symptomatic of middle to late stages of nasopharyngeal carcinoma. For patients with middle to late stages of nasopharyngeal carcinoma, their immunity is compromised, and this decrease in immunity becomes more pronounced after receiving anti-tumor treatments such as radiotherapy and chemotherapy. As a result, patients are highly susceptible to concurrent infections, primarily manifesting symptoms related to the respiratory system such as coughing, sputum production, fever, and chest pain. Additionally, late-stage nasopharyngeal carcinoma patients may also experience metastasis to the lungs. When lung metastasis occurs, patients may develop obstructive pneumonia, which can also lead to the clinical presentation of excessive sputum. Moreover, some patients may exhibit increased sputum production as a side effect of anti-tumor treatments.

Other Voices

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Written by Li Rui
Otolaryngology
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What tests are done for nasopharyngeal carcinoma?

The examination items for nasopharyngeal carcinoma are mainly divided into three types. The first type is imaging examinations, the second type is blood tests, and the third type is endoscopic pathological biopsy. Imaging examinations mainly involve CT or MRI of the nasopharynx and the whole body. If necessary, PET-CT may also be considered to clarify the extent of the condition and determine the presence of neck or distant metastases, which is helpful for diagnosis and adjuvant therapy. The second type involves blood tests, mainly including general biochemical blood tests and virus detection, which can assess the basic functional status of the body. The third type is the endoscopic pathological biopsy, which involves performing a pathological biopsy under nasal endoscopy, primarily to confirm the diagnosis and observe the extent of the lesion in the nasopharynx.

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Written by Deng Bang Yu
Otolaryngology
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How to check for nasopharyngeal carcinoma?

Nasopharyngeal carcinoma is a malignant tumor in the nasal area, clinically mainly squamous cell carcinoma. The incidence of nasopharyngeal carcinoma is relatively high in southern regions of our country. Clinically, the primary treatment is radiotherapy. For diagnosis, the first general step involves using an electronic nasopharyngoscope to examine the nasopharyngeal area for suspicious conditions. Further imaging studies can also be conducted, such as CT scans and MRI scans of the nasopharyngeal area. Through these examinations, if a neoplasm in the nasal area is essentially identified and suspected to be nasopharyngeal carcinoma, an endoscopic examination is conducted where forceps are used to clip tissue for a pathological biopsy. The pathological biopsy determines whether it is definitively nasopharyngeal carcinoma and identifies the type of cancer cells, thus guiding clinical treatment.

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Written by Deng Bang Yu
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What are the symptoms of late-stage nasopharyngeal carcinoma?

Nasopharyngeal cancer is a common malignancy in otolaryngology, primarily located in the nasopharyngeal area. In advanced stages, nasopharyngeal cancer manifests symptoms in two main aspects. One involves symptoms directly caused by the cancer or its metastasis, typically presenting as increased nasal masses, enlarged cervical lymph nodes, severe headaches, decreased hearing, and bleeding in the nasal area due to tumor cells or tissue eroding the internal carotid artery. Additionally, there is a foul smell from the nasopharyngeal area. The second aspect relates to systemic symptoms due to the growth of nasopharyngeal cancer, leading to poor overall nutritional status and cachexia, characterized by extreme emaciation. There is also the potential for distant metastasis of the tumor cells, presenting symptoms in the corresponding areas.

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Written by Zhang Jun
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The Difference between Nasopharyngitis and Nasopharyngeal Carcinoma

The differences between nasopharyngitis and nasopharyngeal carcinoma are very clear. Firstly, nasopharyngitis is an acute inflammatory irritation, while the cause of nasopharyngeal carcinoma is currently unknown, generally associated directly with EB virus infection. Secondly, their clinical manifestations are different. Patients with nasopharyngitis may experience dryness and pain in the nasopharyngeal area, and yellow secretions may occur when clearing the throat in the morning. In contrast, nasopharyngeal carcinoma typically presents as a painless mass. During examination with a nasopharyngoscope, the surface of nasopharyngitis is congested and swollen, whereas in nasopharyngeal carcinoma, cauliflower-like neoplasms or ulcers can be found at the top of the nasopharynx or near the pharyngeal recess. A local pathological examination can reveal symptoms and clarify the diagnosis. In terms of treatment, nasopharyngitis requires symptomatic anti-inflammatory treatment, while nasopharyngeal carcinoma requires local radiotherapy or chemotherapy.

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Treatment of nasopharyngeal carcinoma

Nasopharyngeal cancer is a relatively common type of malignant tumor in the head and neck area. The most commonly used treatment method is primarily radiotherapy, and some patients also need to combine chemotherapy. Overall, most patients can be controlled and relieved after comprehensive treatment with radiotherapy and chemotherapy. Existing clinical evidence shows that for recurrent nasopharyngeal cancer, some patients may consider surgical treatment. However, the indications for surgery are quite narrow and can only be carried out in top hospitals. Therefore, a comprehensive assessment is necessary before further determination and implementation can be considered.