How is nasopharyngeal carcinoma diagnosed?

Written by Deng Bang Yu
Otolaryngology
Updated on September 13, 2024
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Nasopharyngeal carcinoma is a malignant, occupying lesion that occurs in the nasopharyngeal area, and clinically it is mainly squamous cell carcinoma. Relatively speaking, although this tumor is malignant, its degree of malignancy is relatively low, especially when compared to liver cancer, lung cancer, and other malignant tumors. The definitive diagnosis of any tumor primarily relies on histopathological diagnosis, which means that pathological examination is the gold standard. In the case of nasopharyngeal carcinoma, we can make a pathological examination by using nasopharyngeal biopsy tissue with forceps under nasendoscopy. If cancer cells are found, then it is essentially confirmed. Of course, other examination methods, such as CT and MRI, are also helpful in diagnosing nasopharyngeal carcinoma and determining whether there are any metastases.

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The Difference between Nasopharyngitis and Nasopharyngeal Carcinoma

The differences between nasopharyngitis and nasopharyngeal carcinoma are very clear. Firstly, nasopharyngitis is an acute inflammatory irritation, while the cause of nasopharyngeal carcinoma is currently unknown, generally associated directly with EB virus infection. Secondly, their clinical manifestations are different. Patients with nasopharyngitis may experience dryness and pain in the nasopharyngeal area, and yellow secretions may occur when clearing the throat in the morning. In contrast, nasopharyngeal carcinoma typically presents as a painless mass. During examination with a nasopharyngoscope, the surface of nasopharyngitis is congested and swollen, whereas in nasopharyngeal carcinoma, cauliflower-like neoplasms or ulcers can be found at the top of the nasopharynx or near the pharyngeal recess. A local pathological examination can reveal symptoms and clarify the diagnosis. In terms of treatment, nasopharyngitis requires symptomatic anti-inflammatory treatment, while nasopharyngeal carcinoma requires local radiotherapy or chemotherapy.

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Can stage IV nasopharyngeal cancer be cured?

Nasopharyngeal carcinoma is a relatively common type of malignant tumor in the head and neck region. If it is stage IV nasopharyngeal carcinoma, achieving clinical cure is very difficult; only a small portion of patients have the chance to achieve clinical cure, as stage IV nasopharyngeal carcinoma is considered advanced. The current common treatments are a combination of radiotherapy and chemotherapy. During the treatment process, regular reviews are necessary to observe the effects of the treatment. Some patients respond well to the treatment, and the tumor can be completely eliminated after treatment; however, for some patients, the treatment can only control the rapid growth of the tumor, not completely eradicate it. Even if the tumor completely subsides, there might still be a chance of local recurrence or distant metastasis after the treatment ends.

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Is nasopharyngeal carcinoma prone to metastasis?

Nasopharyngeal carcinoma is a relatively common type of malignant tumor in the head and neck area and is prone to metastasis. The most common metastasis site is the cervical lymph nodes. Some patients are diagnosed with nasopharyngeal carcinoma only after the discovery of cervical lymph node metastatic cancer. Additionally, some patients may experience intracranial metastasis or bone metastasis. Generally speaking, for patients with nasopharyngeal carcinoma, it is crucial to achieve early detection, early diagnosis, and early treatment. After treatment, long-term regular follow-up is necessary to help determine the presence of metastasis. Moreover, if metastasis is confirmed, comprehensive treatment should be combined.

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Symptoms of nasopharyngeal carcinoma

Nasopharyngeal carcinoma is a malignant tumor that occurs in the nasopharyngeal area. Typically, nasopharyngeal carcinoma often occurs at the top of the nasopharynx and on the lateral walls of the rhinitis. In the early stages, patients may experience nasal congestion, a runny nose, and upon waking, they might have yellow or bloody discharge. In severe cases, the patient may also experience symptoms such as hearing loss, tinnitus, and ear fullness. If a patient exhibits the aforementioned symptoms, they should first visit a hospital for an electronic nasopharyngoscopy. This can reveal the presence of cauliflower-like neoplasms or ulcers in any part of the nasopharynx. If such findings are observed, a local pathology biopsy is needed. If it is confirmed to be a malignant tumor of the nasopharynx, relevant radiotherapy and chemotherapy treatments are required. Additionally, the patient should also undergo regular systemic examinations to check for distant metastases.

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Treatment of nasopharyngeal carcinoma

Nasopharyngeal cancer is a relatively common type of malignant tumor in the head and neck area. The most commonly used treatment method is primarily radiotherapy, and some patients also need to combine chemotherapy. Overall, most patients can be controlled and relieved after comprehensive treatment with radiotherapy and chemotherapy. Existing clinical evidence shows that for recurrent nasopharyngeal cancer, some patients may consider surgical treatment. However, the indications for surgery are quite narrow and can only be carried out in top hospitals. Therefore, a comprehensive assessment is necessary before further determination and implementation can be considered.