Can people with albinism have eye surgery?

Written by Gao Tian
General Surgery
Updated on September 06, 2024
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Generally, it is possible. Because people with albinism have eyes that are more sensitive to light, mainly because albinism affects the sclera and eyeballs, leading to this condition. However, surgery cannot restore the lost pigmentation in the eyeballs, meaning it is impossible to change the alterations on the eyeballs. It is necessary to prevent strong sunlight exposure, and the only option is to wear sunglasses, which can also reduce the stimulation of ultraviolet rays to the eyes, protect the eyes, reduce external damage, and ensure one can live normally as much as possible. Additionally, this type of disease may lead to malignant skin diseases and other issues due to prolonged exposure to sunlight.

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Written by Zhang Yin Xing
Obstetrics
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How should pregnant women screen for albinism?

Prenatal screening for albinism primarily involves chromosomal testing during pregnancy. Albinism is a single-gene hereditary disease caused by a defect in a single gene. It mainly occurs in children of consanguineous marriages where both parents carry the albinism gene. This is not a routine prenatal screening; it is only conducted if there has been a case of albinism in the family. Fetal chromosomal examination generally takes place between the 16th to 24th weeks of pregnancy during amniocentesis, where fetal cells are collected to conduct genetic testing to determine if the fetus carries the albinism gene.

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Written by Huang Ling Juan
Dermatology
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If vitiligo is not treated, what are the consequences?

If albinism is not treated, it can have serious consequences. Primarily, albinism affects the pigmentation of hair and the retina at the back of the eye. Lack of pigment in the retina can lead to photophobia, and some individuals may experience nystagmus, with severe cases showing a significant decrease in vision. The vision of some individuals with albinism may range between 0.05 to 0.1, which has a significant impact on eyesight. If left untreated, albinism also greatly affects the skin. Individuals with albinism are sensitive to light and are prone to skin cancer under strong ultraviolet radiation. Moreover, some rare types of albinism can cause a decrease in platelet function, leading to a tendency to bleed at a certain age, as well as pulmonary fibrosis. Albinism is primarily a genetic condition caused by mutations and is linked to heredity. The main issue in albinism is a disruption in melanin formation, leading to reduced pigmentation.

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Written by Du Rui Xia
Obstetrics
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Can albinism be detected during pregnancy?

Prenatal genetic testing during pregnancy can be used to diagnose albinism. The incidence of albinism is very low, making it a rare disease clinically, yet it is not included in routine prenatal screening programs. If there are family members with albinism, especially couples who have already had children with the condition, prenatal testing and genetic counseling are necessary. Prenatal genetic testing can identify the specific gene mutation sites within the family. Furthermore, it allows for the use of third-generation IVF techniques to select embryos without the paternal or maternal gene mutations, which can then be implanted in the mother's body to prevent the birth of another child with albinism.

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Written by Yan Xin Liang
Pediatrics
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What causes albinism in infants?

Albinism in infants is caused by a deficiency or dysfunction of tyrosinase, leading to a lack of melanin or a synthesis disorder in the skin and its appendages. This inherited form of albinism results in the retina lacking pigment, with the iris and pupils appearing pale pink, and sensitivity to light. The skin, mucous membranes, hair, and other body hair are white or yellowish-white. Albinism is a familial hereditary disease, inherited as an autosomal recessive trait, often occurring in populations with a high rate of consanguineous marriages. In the genetic pedigree of albinism, both parents carry the albinism gene; carriers themselves do not show symptoms but can pass the causative gene to their children, who then manifest the disease.

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Written by Zhang Jian Bo
Dermatology
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Vitiligo is what kind of disease?

Albinism is a congenital hereditary skin disease, which primarily manifests as the pigment loss or localized, or complete depigmentation of the skin, hair, and eyes. Clinically, it can be categorized into localized albinism and generalized albinism. The onset of the disease may be significantly related to defects in certain genes, hence it has a strong genetic component. Its manifestation includes whitening of the skin and hair, as well as loss of pigment in the eyes. Due to the lack of pigment, symptoms may include photophobia, tearing, and a decrease in vision. Currently, there are no particularly effective treatments for albinism. The main approach includes avoiding light exposure and applying sunblocks and ointments to prevent the occurrence of skin tumors.