How to test for meningitis?

Written by Zhang Hui
Neurology
Updated on September 05, 2024
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Meningitis is a very common disease in neurology, and the most common causes are infections, including viral infections, common bacterial infections, tuberculosis infections, and fungal infections. The main methods of examination for meningitis are as follows: First, physical examination. A physical examination can reveal neck stiffness in the patient, and positive meningeal irritation signs. These examinations are non-invasive and very safe. Second, a lumbar puncture can also be performed. A lumbar puncture can be used to observe whether the fluid pressure is high, and also to collect cerebrospinal fluid to examine its color, perform cytological and biochemical analyses, and culture the cerebrospinal fluid. This is very important to definitively determine the presence of meningitis and to identify the type of infectious agent involved. Additionally, enhanced magnetic resonance imaging can also be performed to see if there is significant enhancement of the meninges.

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Written by Han Shun Li
Pulmonology
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What is meningitis?

Meningitis is predominantly an inflammation that occurs in the meninges and can extend to the brain parenchyma. It is generally caused by pathogenic microorganisms, including common pathogens such as bacteria, fungi, viruses, tuberculosis bacteria, etc. The most common symptoms include fever, headache, nausea, vomiting, stiff neck, etc. More severe cases can present with convulsions, disturbances of consciousness, or even coma. The condition can be mild or severe, and if not treated promptly, it can be fatal in serious cases.

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Written by Liu Shi Xiang
Neurology
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What are the symptoms of meningitis?

The symptoms of meningitis mainly include headache, nausea, vomiting, fever, epileptic seizures, and mental abnormalities. Severe cases may also present with disturbances in consciousness and signs of meningeal irritation, among others. Therefore, when a patient exhibits the above symptoms, the possibility of meningitis should be considered. The patient needs to promptly visit the neurology department to undergo a cranial CT scan, cranial MRI, electroencephalogram, and lumbar puncture for cerebrospinal fluid analysis to confirm the diagnosis. Treatment should be based on the test results, selecting appropriate anti-infective medications. For example, patients with viral meningitis should be treated with antiviral medications such as acyclovir and ganciclovir; patients with bacterial meningitis should be treated with potent antibacterial drugs, including carbapenems and quinolones; patients with tuberculous meningitis should receive antitubercular drugs, such as isoniazid, rifampin, and ethambutol. In addition, patients may also need symptomatic treatments such as dehydration to reduce intracranial pressure, fever reduction, and control of psychiatric symptoms. (Medication should be used under the guidance of a doctor.)

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Written by Han Shun Li
Pulmonology
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Is meningitis scary?

Is meningitis a frightening disease? Meningitis can be very frightening if the condition progresses quickly, or if it is not diagnosed and treated in a timely manner. In severe cases, it can be life-threatening. Many patients often suffer from after-effects following recovery, such as decreased intelligence, dementia, aphasia, paralysis, etc., significantly impacting the quality of life. Therefore, meningitis is a quite frightening disease, and patients should actively cooperate with doctors for treatment to save lives and minimize or reduce the occurrence of after-effects.

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Written by Zhang Hui
Neurology
1min 22sec home-news-image

Differentiation between purulent meningitis and viral meningitis

Purulent meningitis and viral meningitis are different diseases. Purulent meningitis is caused by bacterial infection of the meninges. Viral meningitis is caused by viral invasion of the meninges. Generally, purulent meningitis is more severe, and patients may exhibit symptoms of systemic toxin poisoning, such as high fever, nausea, vomiting, sickly appearance, and general weakness. The symptoms of viral meningitis are relatively mild, and the fever is not particularly severe. Another important differentiation is based on the analysis of cerebrospinal fluid. In viral meningitis, the lumbar puncture shows that the white blood cell count is below 1000*10^6/L, and the levels of sugar and chloride are generally normal or slightly low, with protein usually mildly elevated. In purulent meningitis, the cerebrospinal fluid shows a significant increase in white blood cell count, even reaching from 1000*10^6/L to 10000*10^6/L; the protein content is significantly increased, the sugar content is markedly decreased, and chloride levels are reduced. Additionally, bacteria can be found in the cerebrospinal fluid and blood cultures in purulent meningitis, whereas viral meningitis cerebrospinal fluid cultures do not show bacteria.

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Written by Zhang Hui
Neurology
1min 8sec home-news-image

How to test for meningitis?

Meningitis is a very common disease in neurology, and the most common causes are infections, including viral infections, common bacterial infections, tuberculosis infections, and fungal infections. The main methods of examination for meningitis are as follows: First, physical examination. A physical examination can reveal neck stiffness in the patient, and positive meningeal irritation signs. These examinations are non-invasive and very safe. Second, a lumbar puncture can also be performed. A lumbar puncture can be used to observe whether the fluid pressure is high, and also to collect cerebrospinal fluid to examine its color, perform cytological and biochemical analyses, and culture the cerebrospinal fluid. This is very important to definitively determine the presence of meningitis and to identify the type of infectious agent involved. Additionally, enhanced magnetic resonance imaging can also be performed to see if there is significant enhancement of the meninges.