The main symptom of mammary gland hyperplasia is breast pain, which usually occurs in accordance with the menstrual cycle. There is significant breast pain before the period, and symptoms tend to lessen after the period. Generally, the pain is intermittent, diffuse, dull, or like needle pricks. There can also be shooting pain or hidden pain, and even some report pain as if being cut by a knife. Some of the pain is subjective, but it can also manifest as pain upon touch, or pain from friction caused by clothing during walking. There can be tenderness in the breasts, or increased pain in the upper limbs after physical exertion. The pain may occur in one breast or both.