What causes acute severe pancreatitis?

Written by Li Qiang
Intensive Care Unit
Updated on February 20, 2025
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There are many causes of severe pancreatitis, including the following: The first type is alcoholic pancreatitis, which is caused by heavy drinking leading to pancreatic damage. The second type is pancreatitis due to overeating, where consuming large amounts of food, especially high-fat foods, leads to excessive secretion by the pancreas, resulting in pancreatitis. Another type is biliary pancreatitis, caused by small gallstones from the gallbladder falling into the bile duct. Stones lodged at the opening of the pancreatic and bile ducts cause a secretion disorder in the pancreas, leading to pancreatitis. There is also hyperlipidemic pancreatitis, seen in pregnant women and patients with familial hyperlipidemia. Hyperlipidemia causes blockage of the pancreatic duct, thereby triggering an episode of pancreatitis. Another is traumatic pancreatitis, which is directly caused by external forces leading to compression or contusion injuries of the pancreas. Lastly, there is drug-induced pancreatitis, which occurs when certain medications have a direct toxic effect on the pancreas, causing damage to the pancreatic cells.

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Written by Wu Hai Wu
Gastroenterology
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Can you drink water with acute pancreatitis?

During the acute attack of acute pancreatitis, it is essential to immediately prohibit eating and drinking, as it may exacerbate the condition. Once the abdominal pain disappears and the body temperature normalizes, one can gradually resume eating and drinking, starting with small amounts of water and liquid food. However, it is also necessary to avoid consumption of meats and protein-rich foods. Additionally, if eating prompts a relapse of the condition, it indicates that the prohibition of eating and drinking should continue. If patients with pancreatitis resume eating and drinking too soon, it can lead to a worsening of the condition.

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Written by Zhu Dan Hua
Gastroenterology
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What is acute pancreatitis and is it serious?

Acute pancreatitis is relatively common in clinical practice, which generally refers to inflammatory changes in the pancreas caused by various reasons, such as exudation and necrosis of the pancreas. Depending on the condition, it is divided into mild and severe pancreatitis. Generally, mild pancreatitis has a good prognosis with a treatment period of about one to two weeks through conservative medical treatment, and it typically heals on its own. However, severe pancreatitis with accompanying organ failure, such as liver, kidney, or respiratory failure, or the presence of local complications like abscesses, fever, pseudocysts, obstruction, etc., generally has a longer treatment period, poorer prognosis, and higher treatment costs. Therefore, the treatment outcomes vary depending on the severity and urgency of the acute pancreatitis. It is recommended that patients considering acute pancreatitis should continue diagnosis and treatment at a local hospital. Particular attention must be given to severe pancreatitis.

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Written by Ren Zheng Xin
Gastroenterology
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Can you smoke with acute pancreatitis?

Acute pancreatitis is an emergency related to the pancreas. Smoking during this time is very harmful to health. Nicotine in tobacco directly affects the blood vessels of the pancreas, causing vasoconstriction and exacerbating pancreatitis. During acute pancreatitis, it is necessary to abstain from eating, not consuming any food, and timely use of medications is required to control the infection and decompress the gastrointestinal tract, providing parenteral nutrition. If acute pancreatitis is not treated actively, it can turn into acute suppurative pancreatitis, which poses a risk of shock. Therefore, it is best to be hospitalized for treatment of acute pancreatitis.

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Written by Wu Hai Wu
Gastroenterology
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Can you drink water with acute pancreatitis?

Patients with acute pancreatitis cannot drink water or eat anything during the acute phase. They must undergo gastrointestinal decompression to suction out gastric juice, gastric acid, and gastric contents. At the same time, treatment for acute pancreatitis includes inhibiting pancreatic secretion, anti-infection measures, intravenous fluid replenishment, and maintaining electrolyte balance, among others. If a patient with acute pancreatitis experiences bowel movements, gas, relief from abdominal pain, and a decrease in blood amylase to normal levels, they may then consider drinking small amounts of water and consuming light foods like rice soup or thin porridge. If the abdominal pain disappears, the patient can gradually increase their water intake.

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Written by Jiang Guo Ming
Gastroenterology
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What are the clinical manifestations of acute pancreatitis?

Acute pancreatitis includes two main types: acute edematous pancreatitis and acute necrotizing pancreatitis. It is a common acute and critical condition of the digestive system, particularly acute necrotizing pancreatitis, which can often be life-threatening. The primary symptoms usually include severe upper left abdominal pain, fever, chills, shivering, vomiting, etc. There is a significant relationship between abdominal pain and eating; generally, the pain worsens after eating and can sometimes radiate to the back. The main causes could be binge drinking, overeating, cholecystitis, gallstones, or hyperlipidemia, among others. Diagnosis is usually confirmed through examinations such as an upper abdominal CT and serum and urine amylase tests, followed by appropriate treatment measures.