What is acute severe pancreatitis?

Written by Li Qiang
Intensive Care Unit
Updated on October 20, 2024
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Acute severe pancreatitis is caused by many reasons, including binge eating, especially consuming a large amount of high-fat diet, excessive drinking, obstruction of the pancreatic duct by gallstones in the bile duct, pregnancy, hyperlipidemia, etc. These lead to disorders in pancreatic secretion, resulting in pancreatic juices digesting the pancreas itself and leaking into the abdominal cavity, leading to symptoms such as abdominal effusion. It is classified as severe pancreatitis based on reaching a certain score in some assessments. Severe pancreatitis often accompanies dysfunction of organ systems, common examples include acute respiratory distress syndrome characterized by stubborn hypoxia and respiratory failure, acute renal failure shown by anuria or oliguria, and acute gastrointestinal failure, which manifests as high abdominal pressure and severe intestinal motility disorders, including abdominal distension.

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Written by He Zong Quan
General Surgery
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Causes of vomiting in acute pancreatitis

Acute pancreatitis vomiting has various causes. Firstly, the pancreas is a digestive organ, and upon the onset of pancreatitis, a large amount of pancreatic enzymes is secreted, which significantly affects digestive functions. This easily causes gastrointestinal reactions, and if undigested stomach contents remain in the stomach cavity for too long, it will increase stomach cavity pressure, leading to frequent vomiting. The vomiting caused by acute pancreatitis generally does not alleviate symptoms after vomiting. The treatment primarily targets acute pancreatitis, including enzyme inhibition, acid suppression, and fasting to help reduce vomiting. The occurrence of vomiting is also related to increased intra-abdominal pressure. Following the onset of acute pancreatitis, if treatment is not timely, it can lead to increased intra-abdominal pressure. This increase in pressure can affect gastrointestinal motility, causing reflexive symptoms of nausea and vomiting.

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Written by Wei Shi Liang
Intensive Care Unit
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Is acute severe pancreatitis serious?

Acute severe pancreatitis is a very serious disease in clinical practice, with a high mortality rate, often requiring comprehensive treatment in the ICU. Acute severe pancreatitis is a disease caused by multiple etiologies that results in localized inflammation, necrosis, and infection of the pancreas, accompanied by a systemic inflammatory response and persistent organ failure. It is divided into three phases. The first phase is the acute response phase, occurring from onset to about two weeks, characterized by systemic inflammatory response; the second phase is the systemic infection phase, occurring from two weeks to about two months, characterized by necrosis and infection of the pancreas or peripancreatic tissues; the third phase is the residual infection phase, occurring two to three months later, with clinical manifestations primarily of systemic malnutrition and persistent fistulas, accompanied by gastrointestinal fistulas.

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Written by Li Chang Yue
General Surgery
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Can you drink milk with acute pancreatitis?

Acute pancreatitis, especially in the early stages of an attack, does not allow for the consumption of milk. During the onset of acute pancreatitis, especially at the beginning, it is crucial to completely refrain from eating and drinking anything, as consuming food can lead to excessive secretion of stomach acid. The stimulation from the food can cause the pancreas to secrete enzymes, potentially worsening symptoms like abdominal pain and bloating associated with acute pancreatitis. For patients with acute pancreatitis, if the condition is stable and intestinal function is restored or in the recovery phase, it is permissible to drink some milk. However, it is important to avoid consuming foods that are overly greasy, spicy or stimulating, especially alcoholic beverages, as these can exacerbate the symptoms of pancreatitis or even lead to a recurrence of the condition. The diet should primarily consist of light, low-salt, low-fat fresh vegetables and fruits.

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Written by He Zong Quan
General Surgery
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Differences between acute pancreatitis and acute gastritis

Acute pancreatitis and acute gastritis have somewhat similar symptoms, but there are fundamental differences between them. The onset of pancreatitis is often considered to be caused by biliary, alcoholic sources, or hyperlipidemia, while acute gastritis is mostly related to the stomach being affected by the cold and gastric erosion causing gastritis. During a symptom attack, a comprehensive diagnosis should be made by combining the patient's previous medical history and the characteristics of the symptom onset, as well as laboratory tests and imaging findings. The treatment of acute pancreatitis and acute gastritis also shows distinct differences: acute pancreatitis requires fasting, abstention from drinking, acid suppression, use of magnesium, and correction of fluid and electrolyte balances, along with regular check-ups to prevent the development of pancreatitis. On the other hand, treatment for acute gastritis involves acid suppression and, when necessary, gastric protection.

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Written by He Zong Quan
General Surgery
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Does acute pancreatitis have anything to do with the stomach?

Acute pancreatitis is not closely related to stomach conditions, although it is sometimes associated with overeating, but it is not caused by stomach diseases in patients. Instead, it relates to lifestyle habits. The occurrence of pancreatitis is often considered to be due to biliary, alcoholic, hyperlipidemia, and idiopathic causes. In China, the most common causes are biliary and alcohol-related. Biliary causes are mainly related to gallstones, while alcohol-related causes are mostly associated with drinking. Common stomach diseases include gastritis, ulcers, and stomach cancer. These conditions can sometimes cause an increase in amylase during acute abdominal conditions, but they do not cause acute pancreatitis.