Acute pancreatitis and acute gastritis have somewhat similar symptoms, but there are fundamental differences between them. The onset of pancreatitis is often considered to be caused by biliary, alcoholic sources, or hyperlipidemia, while acute gastritis is mostly related to the stomach being affected by the cold and gastric erosion causing gastritis. During a symptom attack, a comprehensive diagnosis should be made by combining the patient's previous medical history and the characteristics of the symptom onset, as well as laboratory tests and imaging findings. The treatment of acute pancreatitis and acute gastritis also shows distinct differences: acute pancreatitis requires fasting, abstention from drinking, acid suppression, use of magnesium, and correction of fluid and electrolyte balances, along with regular check-ups to prevent the development of pancreatitis. On the other hand, treatment for acute gastritis involves acid suppression and, when necessary, gastric protection.