Pancreatic cancer pain is common in clinical practice, with some patients presenting with abdominal pain as their initial symptom. Pain management can be symptomatic, using analgesics for relief. For mild pain, tramadol can be chosen for pain relief. For severe pain, opioid analgesics such as morphine sustained-release tablets, oxycodone sustained-release tablets, or morphine tablets can be used for pain relief. These are merely symptomatic treatments. The fundamental approach involves surgical or oncological treatments like chemotherapy or radiotherapy to treat pancreatic cancer. Only when the tumor is controlled will the symptoms of pain be alleviated.