Late symptoms of pancreatic cancer include abdominal pain, or sore and swollen back pain, as well as nausea, vomiting, decreased appetite, indigestion, and discomfort of upper abdominal fullness. These are some symptoms affecting the digestive tract. Additionally, there is jaundice caused by tumor compression of the bile duct, as well as skin itching, and even fever. Some patients show clinical manifestations such as ascites when there is metastasis to the liver, or abdominal or retroperitoneal lymph nodes.