Late-stage symptoms of pancreatic cancer

Written by Liu Liang

Oncology

Updated on September 18, 2024

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Late symptoms of pancreatic cancer include abdominal pain, or sore and swollen back pain, as well as nausea, vomiting, decreased appetite, indigestion, and discomfort of upper abdominal fullness. These are some symptoms affecting the digestive tract. Additionally, there is jaundice caused by tumor compression of the bile duct, as well as skin itching, and even fever. Some patients show clinical manifestations such as ascites when there is metastasis to the liver, or abdominal or retroperitoneal lymph nodes.

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Written by Liu Liang

Oncology

57sec

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How is pancreatic cancer diagnosed?

The most common symptoms of pancreatic cancer are pain in the upper abdomen and jaundice. During physical examination, a mass in the upper abdomen can be felt, which is a common symptom. When these symptoms appear, further abdominal ultrasound or CT scans should be performed, as these two are the most commonly used imaging methods for diagnosing pancreatic cancer. Additionally, pancreatic MRI or PET-CT can also help enhance the diagnostic accuracy for pancreatic cancer. MRCP and ERCP are also used to assess the bile ducts and to evaluate the feasibility of surgery. Blood tests for pancreatic cancer-related tumor markers, such as carcinoembryonic antigen (CEA) and CA19-9, are commonly performed, with CA19-9 being particularly sensitive and specific for the diagnosis of pancreatic cancer.

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Written by Wu Hai Wu

Gastroenterology

57sec

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How to deal with lower limb edema in advanced pancreatic cancer?

In late-stage pancreatic cancer, bilateral lower extremity edema should be considered possibly due to hypoalbuminemia, which leads to edema in both legs. It is also possible that cancer emboli in late-stage pancreatic cancer block the venous system, causing impaired venous return and resulting in bilateral lower extremity edema. To determine the specific cause, it is necessary to complete ultrasonographic examinations of the blood vessels in the lower limbs, as well as liver function tests, complete blood count, and others. After clarifying the diagnosis, appropriate treatment measures should be taken based on the different causes. For example, if the edema is caused by hypoalbuminemia, active supplementation with albumin and diuretics, among other treatments, is required. (Note: The use of medications should be carried out under the guidance of a professional doctor.)

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Written by Liu Liang

Oncology

39sec

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Is pancreatic cancer contagious?

Pancreatic cancer, like other malignant tumors, is not contagious. Therefore, in clinical settings, including patients' families and accompanying healthcare staff often ask doctors if they might catch the disease while interacting with cancer patients. It is important to educate that malignant tumors, including pancreatic cancer, are not contagious. Contagious diseases refer to chronic conditions like hepatitis B, hepatitis C, tuberculosis, AIDS, etc., which can spread through contact with bodily fluids or blood of the affected individuals. However, malignant tumors are not infectious.

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Written by Liu Liang

Oncology

44sec

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What should I do if I can't stop vomiting due to pancreatic cancer?

Firstly, we need to ascertain the cause of the vomiting and can provide gastric protection and antiemetic treatment accordingly. If the vomiting is due to biliary obstruction caused by pancreatic cancer, resulting in severe jaundice and intense vomiting, in such cases, we can also place a stent surgically to drain the bile. The jaundice might be relieved afterwards, and accordingly, the vomiting symptoms might also be alleviated. Another aspect is, if the vomiting is caused by the tumor itself due to pancreatic cancer, we need to employ chemotherapy or some targeted or antiangiogenic treatments to control the tumor itself, and only then might the symptoms of vomiting be relieved.

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Written by Yan Chun

Oncology

1min 9sec

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Will the routine blood test be abnormal for pancreatic cancer?

Pancreatic cancer is a malignant tumor of the digestive system. In the early stages, most pancreatic cancer patients generally have normal routine blood test indicators and show no abnormalities. This is because the early lesions are localized, without invasion or metastasis, and therefore have minimal impact on the overall body, not causing abnormalities in routine blood test indicators. As the disease progresses, patients in the middle and late stages of pancreatic cancer often exhibit abnormalities in routine blood test indicators, mainly manifested as abnormalities in hemoglobin levels. Patients experience mild, moderate, or severe anemia. Some patients may also have metastasis to the bone marrow, liver, spleen, etc. Clinically, there can also be a decrease in white blood cells and platelets. Due to the impact of pancreatic cancer lesions on liver function, there can also be abnormalities in coagulation function.