The treatment principles for severe pancreatitis mainly include the following points:

First, closely monitor the patient's heartbeat, respiration, blood pressure, blood oxygen, etc., and if possible, transfer them to the intensive care unit.

Second, maintain electrolyte balance and blood volume, and actively rehydrate.

Third, enhance nutritional support, which can include parenteral nutrition outside of gastrointestinal digestion.

Fourth, routinely use antibiotics in severe pancreatitis to prevent infection from necrotizing pancreatitis.

Fifth, reduce the secretion of pancreatic fluid, inhibit the synthesis of pancreatic enzymes, and suppress the activity of pancreatic enzymes. If the patient develops an infection associated with pancreatic necrosis, consider surgical treatment, etc.