Patients with gallstones experiencing nausea and vomiting is normal, as gallstones often cause acute cholecystitis, leading to pain and discomfort in the upper right abdomen. At this time, it may also affect the stomach causing nausea and vomiting, so it is advisable to use antibiotics for anti-infection treatment as soon as possible. Once the inflammation is controlled, the condition can be alleviated. When nausea and vomiting occur, it is also advisable to fast for gastrointestinal decompression, which can better alleviate the condition. Additionally, after returning to a normal diet, one should avoid spicy and irritating foods to reduce inflammation and aid in the relief of the condition. If symptoms do not improve with conservative treatment, surgery should be considered as soon as possible.