Does iron deficiency anemia cause tiredness?

Written by Zhang Xiao Le
Hematology
Updated on January 15, 2025
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Patients with iron-deficiency anemia can exhibit symptoms of fatigue. Anemia is characterized by red blood cells and hemoglobin levels that are below the normal range. Red blood cells are the main cells responsible for transporting oxygen in the body. Oxygen enters the blood through gas exchange in the lungs and is then delivered throughout the body by red blood cells to supply oxygen. Therefore, patients with anemia will show varying degrees of ischemia and hypoxia. In the nervous system, this can be manifested as lethargy, insomnia, frequent dreaming, tinnitus, blurry vision, fainting, and lack of concentration. As the severity of anemia increases, these symptoms may also worsen. Patients with severe anemia may exhibit significant lethargy and drowsiness.

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Written by He Li Fang
Hematology
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Symptoms of iron deficiency anemia

The clinical manifestations of iron deficiency anemia consist of symptoms due to the anemia itself, specific manifestations of iron deficiency, and the underlying diseases causing the iron deficiency. The onset of anemia is often insidious, with some patients progressing very slowly. Initially, patients can adapt well to daily life and continue with their work, making it difficult to detect. It is usually not until the anemia becomes moderate to severe and symptoms become apparent that it is discovered. Common symptoms of anemia include dizziness, headaches, weakness, easy fatigue, palpitations, and shortness of breath after activity. Some patients might also experience a decline in memory and suffer from tinnitus and blurred vision. Some affected children may exhibit delayed growth and development or even abnormal behaviors, which can manifest as irritability, restlessness, inattention in class, and declining academic performance. A few patients may develop pica, a specific manifestation of iron deficiency anemia. Additionally, some patients might suffer from angular cheilitis, glossitis, and even atrophy of the tongue papillae. Severe cases can experience transient blindness and fainting, hence it is crucial to seek medical attention for iron deficiency anemia at the earliest.

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Written by He Li Fang
Hematology
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Diet for Iron Deficiency Anemia

Patients with iron-deficiency anemia need to undergo pharmacological treatment with oral or injective iron supplements. In addition, patient health education should be enhanced to guide them in following a scientific and reasonable diet. For example, patients who are picky eaters or have insufficient intake should change their dietary structure and lifestyle in order to increase iron intake and bioavailability. This ensures that all key nutrients involved in the production of red blood cells are sufficient. Moreover, it is necessary to increase the intake of iron-rich foods, mainly including animal liver, blood, as well as soybeans, black fungus, egg yolks, brown sugar, lean meat, sheep kidneys, dried fruits, and sesame paste.

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Written by He Li Fang
Hematology
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Characteristics of iron deficiency anemia blood picture

The clinical manifestations of iron deficiency anemia are due to the specific characteristics of anemia caused by iron deficiency and the underlying disease causing the iron deficiency. Its hematological characteristics present as typical microcytic hypochromic anemia. What does this concept mean? It refers to the values in a complete blood count where MCV is less than 80 femtoliters, MCH is less than 27 picograms, and MCHC is less than 30%. MCV refers to the average red blood cell volume, MCH refers to the mean corpuscular hemoglobin concentration, and MCHC refers to the mean corpuscular hemoglobin concentration of red blood cells. The extent of changes in red blood cell indices correlates with the duration and severity of anemia. The blood smear typically shows pale-stained red blood cells with an enlarged central pallor and varying sizes. Platelet count often tends to be high when there is concurrent bleeding and generally tends to be low in infants and children. White blood cell count is usually normal or slightly reduced, with normal differential. These are the hematological characteristics of iron deficiency anemia.

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Written by Zhang Xiao Le
Hematology
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Does iron deficiency anemia cause a yellow complexion?

No matter what type of anemia, it manifests as a decrease in hemoglobin. Red blood cells are the main cells that carry oxygen, so patients with anemia will have signs of ischemia and hypoxia to some extent, and anemia manifests as pallor in the skin and mucous membranes. Since Chinese are of the yellow race, the manifestation of anemia in Chinese patients often appears as a yellowish complexion. Therefore, patients with iron deficiency anemia can have a yellowish complexion. Of course, if there is obvious yellowing of the skin and sclera in addition to the yellowish complexion, further tests such as hemolysis indicators are needed to rule out hemolytic anemia, as patients with hemolytic anemia often have concurrent jaundice.

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Written by Li Guo Bao
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Can iron deficiency anemia be cured?

Iron deficiency anemia is one of the most common types of anemia clinically. The principle of treating iron deficiency anemia involves etiological treatment and symptomatic treatment. Etiological treatment means treating according to different causes, while symptomatic treatment involves correcting anemia and supplementing the raw materials for blood formation. The most common causes of iron deficiency anemia include gastrointestinal bleeding, internal hemorrhoids bleeding, hookworm and roundworm infections, malnutrition, and, notably in women, excessive menstrual bleeding and excessive bleeding during pregnancy and childbirth. These are common causes of iron deficiency anemia seen clinically. With the cause of iron deficiency anemia identified, the treatment often has a relatively high cure rate.