What indicators are used to diagnose iron deficiency anemia?

Written by Li Fang Fang

Hematology

Updated on March 08, 2025

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For iron deficiency anemia, a complete blood count should first be considered. The blood count presenting as microcytic hypochromic anemia often suggests the possibility of iron deficiency anemia. Microcytic hypochromic anemia is characterized by a decrease in hemoglobin, a decrease in mean corpuscular volume, a decrease in mean corpuscular hemoglobin concentration, and a decrease in mean corpuscular hemoglobin. When the complete blood count indicates the possibility of iron deficiency anemia, further investigation into iron-related indices is required, such as decreased serum iron, decreased ferritin, decreased transferrin saturation, and increased soluble transferrin receptor capacity.

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Written by Zhang Xiao Le

Hematology

52sec

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Hazards of Iron Deficiency Anemia in Women

The harm of iron deficiency anemia in women is related to the severity of the anemia. Mild anemia generally has no obvious clinical symptoms; moderate anemia often presents with fatigue, palpitations and shortness of breath after activity, dizziness, tinnitus, insomnia, frequent dreams, reduced appetite, and poor digestive function; severe anemia can affect the quality of life, with symptoms of palpitations and shortness of breath even with slight activity, and can severely impact the quality of life. The most common cause of iron deficiency anemia in women is due to increased menstrual flow. Additional examinations, such as gynecological ultrasound, are necessary to clarify the presence of conditions like uterine fibroids or adenomyosis, and to provide targeted treatment.

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Written by He Li Fang

Hematology

1min 25sec

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How is iron deficiency anemia diagnosed?

The diagnosis of iron deficiency anemia includes two aspects: one is to establish whether there is anemia caused by iron deficiency, and the other is to clarify the cause of the iron deficiency. First, we need to carefully inquire and analyze the medical history, combined with the patient's physical examination, which can provide a series of clues for diagnosing iron deficiency anemia. A definitive diagnosis also requires laboratory evidence. Clinically, we can divide iron deficiency and iron deficiency anemia into three stages: iron deficiency, iron-deficient erythropoiesis, and iron deficiency anemia. The following describes the diagnostic criteria for iron deficiency anemia specifically. Iron deficiency anemia is characterized by a significant reduction in hemoglobin in red blood cells, presenting as microcytic hypochromic anemia. Its diagnostic basis includes three aspects: first, conforming to the diagnosis of iron deficiency and iron-deficient erythropoiesis; second, having microcytic hypochromic anemia; and third, effective treatment with iron supplements. These three factors together can confirm the diagnosis of this disease.

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Written by He Li Fang

Hematology

1min 1sec

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Iron deficiency anemia clinical symptoms

The clinical manifestations of iron deficiency anemia include symptoms caused by ischemia-induced tissue and organ hypoxia, as well as specific clinical signs associated with iron deficiency. Common clinical manifestations of iron deficiency anemia often include dizziness, headache, fatigue, easy tiring, memory decline, shortness of breath and palpitations after activities, and even symptoms such as tinnitus and blurred vision. Specific signs of iron deficiency include stomatitis, glossitis, atrophic gastritis, dry skin, brittle and falling hair, flat or spoon-shaped nails that are thin and prone to cracking. Some patients may also experience pica and difficulty swallowing, all of which are clinical manifestations of iron deficiency anemia.

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Written by He Li Fang

Hematology

1min 19sec

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Can people with iron deficiency anemia drink tea?

The first aspect of treating patients with iron deficiency anemia is etiological treatment. It is necessary to remove the causes of iron deficiency as much as possible. While simple iron supplementation can restore blood indices, if the primary disease is not actively treated, it cannot fundamentally solve anemia. If left untreated, anemia in patients is prone to recurrence. Secondly, iron supplementation is the clinical priority, with oral iron supplements being the most commonly used treatment. Ferrous preparations such as ferrous succinate and ferrous fumarate are most often used. These medications are generally taken with meals or after meals to reduce gastrointestinal irritation. This raises the issue of whether patients with iron deficiency anemia can drink tea. When iron supplements are taken with tea, they can bind with the tannins in the tea to form an insoluble precipitate that is difficult to absorb. Thus, it is clinically advised that patients with iron deficiency anemia should avoid drinking tea, as it can reduce the absorption of iron and thus result in suboptimal treatment outcomes.

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Written by He Li Fang

Hematology

1min 26sec

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Characteristics of iron deficiency anemia blood picture

The clinical manifestations of iron deficiency anemia are due to the specific characteristics of anemia caused by iron deficiency and the underlying disease causing the iron deficiency. Its hematological characteristics present as typical microcytic hypochromic anemia. What does this concept mean? It refers to the values in a complete blood count where MCV is less than 80 femtoliters, MCH is less than 27 picograms, and MCHC is less than 30%. MCV refers to the average red blood cell volume, MCH refers to the mean corpuscular hemoglobin concentration, and MCHC refers to the mean corpuscular hemoglobin concentration of red blood cells. The extent of changes in red blood cell indices correlates with the duration and severity of anemia. The blood smear typically shows pale-stained red blood cells with an enlarged central pallor and varying sizes. Platelet count often tends to be high when there is concurrent bleeding and generally tends to be low in infants and children. White blood cell count is usually normal or slightly reduced, with normal differential. These are the hematological characteristics of iron deficiency anemia.