What indicators are used to diagnose iron deficiency anemia?

Written by Li Fang Fang

Hematology

Updated on March 08, 2025

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For iron deficiency anemia, a complete blood count should first be considered. The blood count presenting as microcytic hypochromic anemia often suggests the possibility of iron deficiency anemia. Microcytic hypochromic anemia is characterized by a decrease in hemoglobin, a decrease in mean corpuscular volume, a decrease in mean corpuscular hemoglobin concentration, and a decrease in mean corpuscular hemoglobin. When the complete blood count indicates the possibility of iron deficiency anemia, further investigation into iron-related indices is required, such as decreased serum iron, decreased ferritin, decreased transferrin saturation, and increased soluble transferrin receptor capacity.

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Written by He Li Fang

Hematology

2min 6sec

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The causes of iron deficiency anemia

The causes of iron deficiency anemia primarily refer to the disruption of the normal dynamic balance between iron absorption and excretion, leading to the consumption of stored iron as well as an increased need for iron and insufficient iron intake, especially in cases of chronic blood loss, resulting in a long-term negative iron balance. The causes of iron deficiency can be divided into two main aspects: insufficient iron intake and excessive iron loss. In the first aspect, decreased iron intake includes dietary insufficiency, meaning inadequate food intake, and reduced absorption, which includes decreased absorption due to lack of stomach acid and reduced absorption following gastric surgery. Excessive iron loss includes the following eight aspects: 1) gastrointestinal bleeding, which includes bleeding caused by tumors, gastrointestinal ulcers, gastritis, as well as bleeding due to parasites and hookworm infections. It also includes bleeding caused by hemorrhoids in men and arteriovenous malformations; 2) excessive menstrual bleeding; 3) frequent blood donations; 4) multiple pregnancies in women; 5) chronic intravascular hemolysis causing hemoglobinuria; 6) hereditary hemorrhagic telangiectasia; 7) primary pulmonary hemosiderosis; and 8) coagulation disorders or the use of anticoagulants leading to iron deficiency. These eight categories all result from excessive loss of iron, causing iron deficiency which leads to iron deficiency anemia.

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Written by He Li Fang

Hematology

1min 41sec

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Should I take vitamin C for iron deficiency anemia?

Patients with iron deficiency anemia mostly suffer from anemia due to lack of iron, but in a small proportion of cases, the essence of their anemia is due to the number of red blood cells or hemoglobin per unit volume of blood being below normal levels. Therefore, any factor that can lead to reduced production or excessive destruction, or loss of red blood cells or hemoglobin can cause anemia. Can patients with iron deficiency anemia consume vitamin C? The main treatment plan for iron deficiency anemia includes four aspects. First, general treatment aims to prevent and reduce various factors that induce iron deficiency. Second, etiological treatment involves identifying a cause whenever possible and controlling the primary iron deficiency related to that cause, such as actively combatting hookworm infection in cases of hookworm disease, stopping bleeding and actively treating ulcers in cases of ulcerative bleeding, and actively controlling menstrual flow in women with heavy periods. Third is the supplementation of iron, which should ideally be taken with vitamin C as it can enhance the absorption of iron. Therefore, patients with iron deficiency anemia can indeed consume vitamin C.

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Written by Li Guo Bao

Hematology

50sec

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Can iron deficiency anemia be cured?

Iron deficiency anemia is one of the most common types of anemia clinically. The principle of treating iron deficiency anemia involves etiological treatment and symptomatic treatment. Etiological treatment means treating according to different causes, while symptomatic treatment involves correcting anemia and supplementing the raw materials for blood formation. The most common causes of iron deficiency anemia include gastrointestinal bleeding, internal hemorrhoids bleeding, hookworm and roundworm infections, malnutrition, and, notably in women, excessive menstrual bleeding and excessive bleeding during pregnancy and childbirth. These are common causes of iron deficiency anemia seen clinically. With the cause of iron deficiency anemia identified, the treatment often has a relatively high cure rate.

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Written by He Li Fang

Hematology

1min 14sec

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Iron deficiency anemia lacks iron.

Iron deficiency anemia is an anemia caused by the lack of stored iron in the body, affecting the synthesis of hemoglobin. It is characterized by a lack of stainable iron in the bone marrow, liver, spleen, and other organ tissues, as well as decreased serum iron concentration, transferrin saturation, and ferritin levels, typically presenting as microcytic hypochromic anemia. Thus, iron deficiency anemia refers to a deficiency of iron. Iron is an essential trace element in the human body, involved in cellular functions and metabolic processes. The body has a strict regulatory mechanism for iron metabolism to ensure that iron levels are always maintained at a normal level, referred to as iron homeostasis. Iron homeostasis relies crucially on the balance between intestinal iron absorption and the body's iron requirements. Once this balance is disrupted, problems in iron distribution, absorption, transport, and storage may occur, leading to iron deficiency anemia.

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Written by Li Fang Fang

Hematology

40sec

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Is donkey-hide gelatin effective for iron deficiency anemia?

Oral consumption of donkey-hide gelatin is ineffective for iron deficiency anemia. Iron deficiency anemia requires iron supplementation treatment, but while donkey-hide gelatin is rich in collagen, it is not rich in iron, thus it is ineffective for treating iron deficiency anemia through oral consumption. For iron deficiency anemia, a diet rich in iron, such as animal liver, lean meats, and blood products, which are rich in iron, should be pursued. Additionally, it is necessary to avoid strong tea, as it contains tannins that can chelate iron and affect its absorption.