Iron deficiency anemia lacks iron.

Written by He Li Fang
Hematology
Updated on September 28, 2024
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Iron deficiency anemia is an anemia caused by the lack of stored iron in the body, affecting the synthesis of hemoglobin. It is characterized by a lack of stainable iron in the bone marrow, liver, spleen, and other organ tissues, as well as decreased serum iron concentration, transferrin saturation, and ferritin levels, typically presenting as microcytic hypochromic anemia. Thus, iron deficiency anemia refers to a deficiency of iron. Iron is an essential trace element in the human body, involved in cellular functions and metabolic processes. The body has a strict regulatory mechanism for iron metabolism to ensure that iron levels are always maintained at a normal level, referred to as iron homeostasis. Iron homeostasis relies crucially on the balance between intestinal iron absorption and the body's iron requirements. Once this balance is disrupted, problems in iron distribution, absorption, transport, and storage may occur, leading to iron deficiency anemia.

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Written by He Li Fang
Hematology
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Iron deficiency anemia should see which department?

Anemia is a condition characterized by a reduction in the total volume of red blood cells in the circulating blood to below normal levels. Iron deficiency anemia is a type of anemia caused by a lack of raw materials for blood production. Iron deficiency anemia occurs when the body's stored iron is depleted and cannot meet the needs for normal red blood cell production. Iron deficiency anemia is a common type of red blood cell disease and falls within the category of hematology. Therefore, patients with iron deficiency anemia should seek treatment in the department of hematology.

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Iron deficiency anemia clinical manifestations

Iron deficiency anemia presents in a variety of ways, including symptoms of anemia and iron deficiency. The main manifestation is tissue and organ hypoxia caused by iron deficiency, and severe iron deficiency anemia can lead to mucosal tissue changes and ectoderm nutritional disorders. Among the symptoms, we can find that in the early stages, the symptoms are relatively concealed and hard to detect. Patients with a slow progression can often adapt well in the early stages and are able to engage in daily work. Common symptoms of anemia include dizziness, headache, fatigue, and tiredness, along with palpitations and shortness of breath after activity, and even symptoms such as blurred vision and tinnitus. For patients with iron deficiency, specific symptoms include angular cheilitis, atrophy of the tongue papillae, glossitis, and severe iron deficiency patients may experience koilonychia, decreased appetite, nausea, and even constipation. Some patients, particularly children during their growth periods, may exhibit delayed growth and behavioral abnormalities, specifically being irritable and easily angered, having difficulty concentrating in class, and declining academic performance. A few patients may also develop pica, which is a special manifestation of iron deficiency anemia. In terms of physical signs, patients may exhibit pallor of the skin and mucous membranes, dry hair, and keratinization of the lips. Nails may be flat, lackluster, and prone to breakage, and a small number of patients may experience mild splenomegaly. These are the clinical manifestations of iron deficiency anemia.

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Hematology
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Characteristics of iron deficiency anemia blood picture

The clinical manifestations of iron deficiency anemia are due to the specific characteristics of anemia caused by iron deficiency and the underlying disease causing the iron deficiency. Its hematological characteristics present as typical microcytic hypochromic anemia. What does this concept mean? It refers to the values in a complete blood count where MCV is less than 80 femtoliters, MCH is less than 27 picograms, and MCHC is less than 30%. MCV refers to the average red blood cell volume, MCH refers to the mean corpuscular hemoglobin concentration, and MCHC refers to the mean corpuscular hemoglobin concentration of red blood cells. The extent of changes in red blood cell indices correlates with the duration and severity of anemia. The blood smear typically shows pale-stained red blood cells with an enlarged central pallor and varying sizes. Platelet count often tends to be high when there is concurrent bleeding and generally tends to be low in infants and children. White blood cell count is usually normal or slightly reduced, with normal differential. These are the hematological characteristics of iron deficiency anemia.

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Iron deficiency anemia has the following symptoms:

The clinical manifestations and symptoms of iron deficiency anemia mainly include symptoms of both anemia and iron deficiency. Symptoms in patients with anemia often include dizziness, headache, shortness of breath and palpitations after activity, difficulty concentrating, easy fatigue, blurred vision, tinnitus, and other symptoms. There are also specific signs of iron deficiency such as cheilitis, glossitis, and atrophy of the tongue papillae. In terms of physical signs, we can find that some patients may have spoon nails. Regarding appetite, some patients may experience reduced appetite, nausea, and even constipation, all of which are general symptoms of iron deficiency anemia. Severe cases may even exhibit transient syncope, visual obscurity, and pica as clinical manifestations.

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Which department should I go to for iron deficiency anemia?

The formed elements in the blood include red blood cells, white blood cells, and platelets, which play important roles in cellular metabolism, defense, and hemostasis, respectively. Among them, anemia falls under the category of red blood cell diseases. Iron-deficiency anemia refers to a condition where the body's iron stores are depleted, failing to meet the needs for normal red blood cell production. Before the production of red blood cells is restricted, the body's iron stores are already depleted, but anemia has not yet occurred, a condition we call iron deficiency, also known as the subclinical iron deficiency period clinically. Iron-deficiency anemia is a common red blood cell disease and falls under the category of hematology. Therefore, patients with iron-deficiency anemia should consult a specialist in hematology.