Vulvar cancer is a type of malignant tumor in women's gynecology, which has a relatively low clinical incidence rate. For stage III vulvar cancer, it is considered advanced vulvar cancer. Advanced vulvar cancer indicates that the lesion has spread. For vulvar cancer with lesion spread, surgical treatment should be pursued if possible. For patients who cannot undergo surgery, options like chemotherapy, radiotherapy, targeted therapy, and other comprehensive combined treatment methods can be considered for cancer treatment. However, for patients with advanced vulvar cancer, the aim of treatment is mainly to improve the quality of life and extend the survival time, as complete clinical cure of the tumor is not possible. Only early-stage vulvar cancer, after receiving curative surgery or curative radiotherapy, may achieve a clinically cured effect.