Patent ductus arteriosus usually does not cause mitral regurgitation.

Since the pressure in the aorta is greater than that in the pulmonary artery, blood from the aorta will shunt to the pulmonary artery, significantly increasing blood flow in the pulmonary circulation. This eventually leads to pulmonary hypertension, causing an increased afterload on the right ventricle. Over time, an increased afterload on the right ventricle can lead to right ventricular enlargement and right heart failure, resulting in dilation of the tricuspid annulus and tricuspid regurgitation due to incomplete closure.

Patients with patent ductus arteriosus need to seek prompt medical assessment to determine the need for surgical treatment. For patients with surgical indications, surgery should be administered promptly to avoid the adverse consequences of long-term blood shunting.