Patients with lung cancer presenting with dry cough and wheezing often require treatment to suppress coughing, alleviate wheezing, and address the symptoms. It is also important to check if the patient has concurrent obstructive pneumonia. Lung cancer combined with obstructive pneumonia can also lead to dry cough and wheezing. In such cases, anti-infection treatment is needed, along with treatment specifically targeting lung cancer itself. Dry cough and wheezing in lung cancer often suggest that the cancer may be in the middle to late stages, where the chances of surgery are generally small. However, it is still necessary to complete relevant examinations to further assess the condition. If the patient is eligible for surgery, surgical treatment should be considered. If the patient is indeed in the middle to late stages of lung cancer and is not suitable for surgery, chemotherapeutic drugs are needed for treatment. Sometimes, targeted drugs can be chosen for treating advanced-stage non-small cell lung cancer. In cases of advanced non-small cell lung cancer with driver gene mutations, targeted therapy might even be the preferred treatment option.