Does early-stage lung cancer cause chest pain?

Written by Yuan Qing
Pulmonology
Updated on July 04, 2025
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Early-stage lung cancer does not cause chest pain. Early-stage lung cancer actually refers to precancerous lesions or the very earliest stage of the disease. Generally, early-stage lung cancer occurs within the lung parenchyma or the airway lumen. Typically, there are no sensory nerves in the airway lumens or lung parenchyma, and without sensory nerve distribution, there won't be any pain.

Of course, if the lung cancer grows to a certain extent and affects the pleura, it can cause chest pain because there are nerves, especially sensory nerves, distributed on the pleura. However, if it involves the pleura, it can no longer be called early-stage lung cancer, as it often indicates that the cancer has progressed to the middle or late stages.

Therefore, generally speaking, early-stage lung cancer in the lung parenchyma absolutely does not cause chest pain, so there is no need to worry.

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How to stop coughing and wheezing in the late stage of lung cancer

Lung cancer is a relatively common type of malignant lung tumor clinically. Due to the different specific types of lung cancer in different populations, the symptoms experienced by patients also vary. In the early stages of lung cancer, symptoms are generally characterized by irritative dry cough, hemoptysis, breathlessness, and chest tightness. As the tumor grows and metastasizes, patients in the later stages may experience varying degrees of coughing, wheezing, and expectoration. For such patients, the first step is to provide appropriate anti-infection treatment and oral administration of antispasmodic drugs. Inhalation of medications that relieve bronchospasm can also be chosen, both of which can achieve a certain effect in relieving cough and easing breathing.

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Staging of Lung Cancer

The staging of lung cancer is of great clinical significance for the selection of clinical treatment plans and the prediction of prognosis. According to the International Association for the Study of Lung Cancer and the World Health Organization, lung cancer is staged based on the size of the primary tumor (T stage), the condition of tumor lymph node metastasis (N stage), and the presence of distant metastases (M stage). Lung cancer is classified according to these criteria, which are used internationally. Currently, there are UICC staging and AJCC staging, which are two different systems.

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How is lung cancer detected?

For lung cancer detection, it is recommended for individuals over forty, especially smokers, to undergo a low-dose spiral CT for screening. Secondly, if someone has been a long-term heavy smoker and has undergone chest X-rays and low-dose spiral CT and a lung mass is found, it is suggested that the patient undergo a contrast-enhanced CT or a PET-CT to determine the condition and location of the lung mass. After establishing the condition and location, a sputum cytology test can be conducted. Thirdly, to confirm whether it is lung cancer, one should undergo bronchoscopy to obtain a biopsy, or a transthoracic lung puncture biopsy, or examine live tissue or metastatic lesions, or perform a pleural fluid examination to detect the cancer cells and determine the specific type of lung cancer to guide treatment. However, if the nature of the lesion cannot be clearly determined through mediastinoscopy, bronchoscopy, chest wall puncture biopsy, or other methods, a thoracotomy exploration is recommended. Additionally, the examination of tumor markers cannot be ignored.

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Does lung cancer cause coughing?

The most common symptoms of lung cancer patients include coughing, followed by coughing up blood, difficulty breathing, and chest pain. When the tumor grows in larger bronchi, it often causes an irritable cough, which can easily be mistaken for a cold. As the tumor continues to grow and affects the drainage of the bronchi, secondary lung infections can occur, possibly producing purulent sputum and an increased amount of coughed-up sputum. At this time, coughing becomes quite severe. Another symptom that may appear is blood in the sputum, which could be blood-streaked sputum, or sporadic, small amounts of coughed-up blood.

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Symptoms of advanced lung cancer

Late-stage lung cancer may cause pain. For example, bone metastasis is a common site of metastasis for lung cancer, which can lead to pain; if it metastasizes to the liver, it can cause expansive pain in the liver, and chest tightness and shortness of breath are also common symptoms of late-stage lung cancer. If the tumor is located at the hilum of the lung, compressing the lobar bronchi, main bronchus, etc., compression can lead to corresponding lung collapse, possibly causing chest tightness and shortness of breath. Additionally, a large amount of pleural effusion can also occupy the thoracic cavity, compressing the lungs, leading to difficulties in breathing due to chest tightness. Coughing might be a common symptom in lung cancer patients, especially in those whose tumors are located at the hilum of the lung. Hoarseness is caused by compression of the recurrent laryngeal nerve, and this symptom might be alleviated after tumor treatment. Furthermore, some patients with advanced-stage lung cancer may experience swelling of the upper limbs and face, which is caused by the tumor compressing the superior vena cava.