Late-stage lung cancer may cause pain. For example, bone metastasis is a common site of metastasis for lung cancer, which can lead to pain; if it metastasizes to the liver, it can cause expansive pain in the liver, and chest tightness and shortness of breath are also common symptoms of late-stage lung cancer. If the tumor is located at the hilum of the lung, compressing the lobar bronchi, main bronchus, etc., compression can lead to corresponding lung collapse, possibly causing chest tightness and shortness of breath. Additionally, a large amount of pleural effusion can also occupy the thoracic cavity, compressing the lungs, leading to difficulties in breathing due to chest tightness. Coughing might be a common symptom in lung cancer patients, especially in those whose tumors are located at the hilum of the lung. Hoarseness is caused by compression of the recurrent laryngeal nerve, and this symptom might be alleviated after tumor treatment. Furthermore, some patients with advanced-stage lung cancer may experience swelling of the upper limbs and face, which is caused by the tumor compressing the superior vena cava.