What causes lung cancer?

Written by Gong Chun
Oncology
Updated on September 13, 2024
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Lung cancer is caused by a variety of factors. Research indicates that lung cancer results from a combination of genetic defects, external and internal environmental factors, and personal factors. Numerous studies have confirmed that long-term and heavy smoking is the most significant carcinogenic factor for lung cancer. There is a positive correlation between the amount and duration of smoking and the incidence of lung cancer. The second factor is related to working in asbestos-related industries, which very much relates to the work environment, and also has a certain relation to smog. Indoor environmental pollution is also a very significant carcinogenic factor for lung cancer. This includes smoke from burning coal indoors, fumes from cooking oils in kitchens, and carcinogenic substances released by indoor decorating materials. Fourthly, internal human factors such as the immune status, metabolic abnormalities, genetic factors, and chronic lung infections are also related. The fifth factor involves irregular diet and rest habits, irritating foods, alcohol consumption, and heavy smoking.

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Written by Gong Chun
Oncology
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What department should lung cancer patients visit?

The first point is that lung cancer can be categorized as a respiratory system disease, so one could visit the respiratory department. However, the respiratory department is not specialized enough for lung cancer, so it is recommended to visit the oncology department instead. After all, lung cancer is a malignant tumor. Initially, one can visit the respiratory department, but once it is confirmed through biopsy that it is lung cancer, it is advised to seek specialized treatment in the oncology department, as it is a malignant tumor.

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Written by Gong Chun
Oncology
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How is lung cancer detected?

For lung cancer detection, it is recommended for individuals over forty, especially smokers, to undergo a low-dose spiral CT for screening. Secondly, if someone has been a long-term heavy smoker and has undergone chest X-rays and low-dose spiral CT and a lung mass is found, it is suggested that the patient undergo a contrast-enhanced CT or a PET-CT to determine the condition and location of the lung mass. After establishing the condition and location, a sputum cytology test can be conducted. Thirdly, to confirm whether it is lung cancer, one should undergo bronchoscopy to obtain a biopsy, or a transthoracic lung puncture biopsy, or examine live tissue or metastatic lesions, or perform a pleural fluid examination to detect the cancer cells and determine the specific type of lung cancer to guide treatment. However, if the nature of the lesion cannot be clearly determined through mediastinoscopy, bronchoscopy, chest wall puncture biopsy, or other methods, a thoracotomy exploration is recommended. Additionally, the examination of tumor markers cannot be ignored.

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Written by An Yong Peng
Pulmonology
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Is coughing severe in the early stages of lung cancer?

Patients with lung cancer in the early stages may experience severe coughing, mild coughing, or no coughing symptoms at all. Many early-stage lung cancer patients have lesions located near the periphery of the lungs that do not involve the airways or other significant structures, typically resulting in no clinical symptoms. By the time clinical symptoms appear, the patient may already be in the middle or late stages of lung cancer. Additionally, it is important to note that some patients with early-stage lung cancer may also experience coughing, which can range from severe to mild, and may include coughing up blood. Such symptoms are often seen in early-stage central lung cancer, which frequently presents with cough and blood in the sputum. Therefore, older patients with a long history of smoking who suddenly develop a cough or start coughing up blood should be highly vigilant and likely need to undergo chest CT scans, bronchoscopy, and other related examinations for evaluation.

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Written by Gong Chun
Oncology
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What is the treatment for lung cancer?

Treatment for lung cancer should be based on the pathological staging, the pathology type, the biological behavior of the lung cancer, and individualization, taking into account the patient's cardiopulmonary function and overall systemic condition to develop a personalized treatment plan. For non-small cell lung cancer and small cell lung cancer, the treatment approaches differ significantly. Therefore, it is advisable for patients to seek treatment at specialized hospitals, under the guidance of oncology specialists. Generally, treatment options for non-small cell lung cancer include surgical resection, adjunctive chemoradiation, neoadjuvant chemoradiation, targeted therapy, and immunotherapy. For small cell lung cancer, a comprehensive treatment plan combining chemoradiation, along with prophylactic cranial irradiation and other aggressive treatments, is recommended. Each individual's situation might differ, so it is important to focus on a personalized comprehensive treatment plan rather than a one-size-fits-all approach.

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Written by Gong Chun
Oncology
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How to check for lung cancer?

How to check for lung cancer, firstly, for lung cancer screening, particularly in people over forty years old, especially smokers, it is recommended to regularly undergo low-dose spiral CT scans of the chest. Secondly, if a tumor is detected, it is suggested to proceed with enhanced CT scans, sputum cytology tests, or PET-CT. If it is confirmed that there is a tumor in the lungs, then a biopsy is needed. The biopsy can be performed under bronchoscopy, or transthoracic lung puncture and biopsy of living tissue can also be done, as well as biopsy of metastatic lesions or cytological examination of pleural effusion to diagnose whether it is lung cancer, the type of lung cancer, and certain immunohistochemical situations.