Causes of ectopic pregnancy

Written by Liu Qin
Obstetrics and Gynecology
Updated on February 03, 2025
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Ectopic pregnancy refers to the implantation of a fertilized egg outside the uterine cavity, among which tubal pregnancy is the most common type, accounting for about 95% of ectopic pregnancies. There are many causes of ectopic pregnancy, with the main cause being inflammation of the fallopian tubes. The inflammation can cause the mucous membrane of the fallopian tube to become sticky, narrowing the lumen of the tube, or impairing the function of the cilia inside the tube, leading to obstruction of the fertilized egg's movement within the tube and resulting in implantation at that location. Other causes include surgery on the fallopian tubes, poor development or abnormal function of the fallopian tubes, further development of assisted reproductive technologies, and the use of emergency contraceptive pills, also known as contraceptive failure, among others. (The use of medications should be under the guidance of a doctor.)

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Written by Liu Qin
Obstetrics and Gynecology
1min 14sec home-news-image

What causes an ectopic pregnancy?

Ectopic pregnancy refers to the implantation of a fertilized egg outside the uterine cavity, with tubal pregnancy being the most common type, accounting for up to 95% of cases. There are many causes of ectopic pregnancy, with the main reasons including the following: First, inflammation of the fallopian tubes is a major cause of ectopic pregnancy because the inflammation can cause the mucous membranes of the tubes to adhere, narrowing of the lumen, or impairment of the cilia function, leading to obstruction of the fertilized egg's movement within the tube, preventing it from reaching the uterine cavity, thus, it implants in the tube. Second, the patient has a history of fallopian tube surgery or a previous ectopic pregnancy. Third, poor development or abnormal function of the fallopian tubes. Fourth, the implementation of assisted reproductive technology. Fifth, the intake of emergency contraceptive pills by individuals who experienced contraceptive failure. (The use of medications should be done under the guidance of Doctor Yan.)

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Written by Zhang Xiu Rong
Obstetrics and Gynecology
1min 10sec home-news-image

Ectopic pregnancy signs

Normally, if menstruation does not occur at the expected time and there is irregular, light bleeding, the first step is to go to the hospital for an early pregnancy test. If the test shows two lines, this indicates pregnancy. Pregnancy includes intrauterine pregnancy and ectopic pregnancy. In cases of ectopic pregnancy, there is generally also irregular bleeding and abdominal pain. Therefore, if the early pregnancy test is positive with two lines and there is irregular bleeding and abdominal pain, one must be alert for the occurrence of an ectopic pregnancy. At this time, you can go to the hospital for blood tests to check the HCG levels and progesterone, along with an ultrasound to comprehensively determine the situation. If there is no gestational sac within the uterine cavity and an abnormal mass is found outside the uterus, then hospitalization and appropriate treatment for the ectopic pregnancy are needed.

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Written by Zhang Lu
Obstetrics
1min 21sec home-news-image

ectopic pregnancy symptoms

Ectopic pregnancy is not a normal state of pregnancy. Normally, the gestational sac should be located in the middle of the uterine cavity. An ectopic pregnancy refers to the implantation of the gestational sac outside the uterine cavity. Common types of ectopic pregnancy include tubal pregnancy, ovarian pregnancy, and abdominal pregnancy, with over 99% of ectopic pregnancies being tubal pregnancies. The symptoms of an ectopic pregnancy include the following aspects: 1. In the early stages of an ectopic pregnancy, there are no clinical symptoms because the early gestational sac is relatively small and does not stimulate the fallopian tube or the local area, thus causing no symptoms. 2. When the gestational sac grows to a certain size, it compresses the tube cavity, causing mild abdominal pain. This pain intensifies as the gestational sac grows and can lead to tearing pain, indicating a ruptured tubal pregnancy. 3. During an ectopic pregnancy, because the gestational sac cannot develop normally, the levels of estrogen and progesterone in the body are relatively low, leading to endometrial withdrawal bleeding, which manifests as a small amount of bright red vaginal bleeding.

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Written by Tang Mei Xiang
Obstetrics and Gynecology
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What is an ectopic pregnancy?

Ectopic pregnancy used to be commonly referred to as "宫外孕". In fact, it is known as ectopic pregnancy, which means that the fertilized egg implants outside the uterine cavity. A normal pregnancy occurs in the uterine cavity, but if it occurs outside the uterine cavity, it is called ectopic pregnancy. Ectopic pregnancy includes tubal pregnancy, ovarian pregnancy, abdominal pregnancy, broad ligament pregnancy, cervical pregnancy, cornual pregnancy, etc. These are all types of ectopic pregnancies, with tubal pregnancy being the most common clinically.

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Written by Zhao Li Li
Obstetrics
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Do ectopic pregnancies require surgery?

In general, if an ectopic pregnancy is confirmed, further symptomatic examinations and treatments are necessary. Normally, it is recommended to determine the specific location of the ectopic pregnancy and any changes in vital signs under ultrasound examination. If the patient's vital signs are stable, the ectopic site has not ruptured, and there is no intraperitoneal bleeding, conservative medical treatment can be temporarily administered. If severe intraperitoneal bleeding has occurred, accompanied by changes in vital signs, it is advisable to promptly proceed with surgical treatment.