Causes of Kidney Stones

Written by Hu Lin
Nephrology
Updated on January 01, 2025
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The causes of kidney stone formation include the following: One reason is the increased amount of stone-forming components in the urine. Various factors that cause an increase in the concentration of salts, uric acid, oxalates, and cystine in the urine can exceed their solubility. This results in the precipitation and crystallization from the urine, which further grows into stones. For example, hyperuricemia can lead to an increased excretion of urinary uric acid, making it easy to form urate stones. Secondly, the reduction in urine substances that inhibit stone formation, including decreases in citrate and magnesium, can promote stone formation. Third, urinary tract obstruction and infection can lead to stone formation. In cases of urinary tract obstruction and poor urine flow, small crystals formed in the urine can easily adhere to the epithelial cells of the urinary tract, becoming the nucleus of the stone. Urinary tract obstruction may also lead to urinary tract infections where bacteria, pus, and damaged, necrotic epithelial cells can also form the core of stones and gradually develop into larger stones. Fourth, diet and hydration play significant roles. Long-term, high intake of high-protein, high-sodium, high-sugar foods can cause increased excretion of urinary calcium and uric acid, while reducing citrate levels, thus promoting stone formation. A decrease in water intake can also cause urine concentration, further promoting stone formation. Fifth, environmental factors and genetic factors are considered to be related to the formation of kidney stones. It is believed that the hardness of water and genetic factors also have certain relationships with kidney stone formation.

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Written by Zeng Zhong
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How to relieve the pain of kidney stones

Kidney stones, if mobile within the kidney, can cause intense pain in the patient's lumbar and abdominal area, clinically referred to as renal colic. Patients often experience unbearable pain, heavy sweating, along with symptoms such as nausea and vomiting. In such cases, it is crucial to seek timely treatment at the hospital's urology department. Doctors will use medications to alleviate pain and spasm. If there is nausea and vomiting, antiemetic drugs will also be used to relieve symptoms. Once diagnosed with kidney stones, patients are advised to seek treatment at a hospital as soon as possible.

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Written by Zou De Bo
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What is the best treatment for kidney stones?

Kidney stones are generally treated by drinking a lot of water. Smaller stones may be expelled due to the push of a large volume of urine. Secondly, antispasmodic analgesics like M-type cholinergic receptor blockers can be used to relax the ureteral smooth muscle and alleviate spasms. Thirdly, controlling infection is crucial because urinary tract obstructions caused by stones are prone to infections, and infections often lead to the formation of struvite stones, perpetuating a vicious cycle that exacerbates the condition. It is essential to actively remove obstructions caused by stones and use antibiotics for prevention. Fourth, surgical treatment should be considered when pain cannot be alleviated by medication or when the stone is too large.

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Written by Guan Hai Fang
Urology
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What should be noted for kidney stones?

If you have kidney stones, you should avoid vigorous exercise and heavy physical labor in daily life, and avoid eating foods that may aggravate kidney stones. For example, do not eat persimmons, drink tea, consume tofu, or eat too many soy products, etc. The reason to avoid persimmons is that they contain tannins, which can contact stomach acid and more easily bond with plant fibers, forming a stone that may worsen kidney stones. In other aspects, pay attention to a light diet because inflammation is more likely to occur with kidney stones, so avoid eating spicy and stimulating foods. It is recommended that patients go to a regular hospital for examination and treatment.

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Do you need to be hospitalized for kidney stones?

Patients with kidney stones need to decide on a treatment plan based on the size of the stones, which determines whether hospitalization is necessary. For kidney stones smaller than 1.5 cm, extracorporeal shock wave lithotripsy can be utilized, allowing the patient to avoid hospitalization. After treatment, the patient can go home, where it is advised to engage in physical activity, drink plenty of water, and urinate frequently to facilitate the expulsion of the stones. A follow-up ultrasound of the urinary system should be conducted one week later at the hospital to monitor the status of the stone expulsion. If the stones are larger than 1.5 cm, surgical treatment is required, which necessitates hospitalization.

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What are the symptoms of kidney stones?

The symptoms of kidney stones vary depending on the size and location of the stone, and whether there is associated hydronephrosis. If the stone inside the kidney is relatively small, most patients experience no discomfort, and it is generally discovered during an ultrasound examination at physical check-ups. However, if such a small stone falls into the ureter, it can irritate the ureteral walls and cause ureteral spasms, resulting in renal colic and, in some cases, hematuria. If the kidney stone is relatively large and causes kidney hydronephrosis or even pyonephrosis, the patient will experience sour swelling and pain in the waist on the side of the stone. If an infection occurs, symptoms such as chills and high fever may also appear.