Causes of Anemia in Late Pregnancy

Written by Yue Hua
Obstetrics and Gynecology
Updated on September 08, 2024
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Anemia can be categorized into several different types, each caused by different reasons. Iron-deficiency anemia occurs in late pregnancy when the intake or absorption of iron by pregnant women is insufficient. Megaloblastic anemia is caused by a deficiency of folate or vitamin B12 in the patient's body. Additionally, there is thalassemia, which is caused by a genetic deficiency in the patient, leading to anemia in the fetus as well. Another type is aplastic anemia, which is caused by abnormal bone marrow hematopoietic function leading to anemia.

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Written by Liu Wei Jie
Obstetrics
1min 6sec home-news-image

What should pregnant women do about anemia?

We often find that anemia in pregnant women is very common during prenatal check-ups. There are three main reasons for anemia. The first reason is iron deficiency anemia, which is due to insufficient intake during pregnancy while the fetus requires a large amount, leading to iron deficiency anemia. The second reason is megaloblastic anemia, which is caused by insufficient intake of vitamin B6 and folic acid, resulting in anemia. Another condition is thalassemia, which is due to a genetic mutation causing anemia. For treatment of anemia, we first need to address the specific cause. If it is iron deficiency anemia, iron supplements are necessary, and the diet should include foods like pork liver and lean meat. If it is megaloblastic anemia, supplementation with folic acid and vitamin B12 is needed. Moreover, for thalassemia, mild cases can be observed, while severe cases may require a small amount of blood transfusion treatment.

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Written by Li Fang Fang
Hematology
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How is anemia treated?

For any type of anemia, if the anemia is severe, there is a need for active transfusion of red blood cells to correct the anemia. However, anemia can reoccur after transfusion of red blood cells, and it is not a long-term solution. Therefore, after correcting anemia with red blood cell transfusion, it is still necessary to diagnose the specific cause of the anemia and treat it accordingly. For example, patients with iron deficiency anemia need iron supplementation, those with megaloblastic anemia need to be supplemented with folic acid and vitamin B12, and patients with acute blood loss anemia need to find the source of bleeding and receive hemostatic treatment. Anemia caused by malignant hematological disorders like acute leukemia or myelodysplastic syndromes requires anti-tumor treatment.

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Written by Li Fang Fang
Hematology
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Anemia lacks what element

Anemia is not always caused by a deficiency in elements. In cases of iron deficiency anemia, it is due to a lack of iron. Megaloblastic anemia occurs because of a deficiency in folate or vitamin B12. However, clinically, there are many other types of anemia, such as aplastic anemia, hemolytic anemia, myelodysplastic syndromes, leukemia, etc. The anemia caused by these diseases is not due to a deficiency in elements, but is due to the diseases themselves affecting bone marrow hematopoiesis, leading to anemia. Therefore, it is necessary to clearly diagnose the cause of anemia in order to treat it effectively.

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Written by Li Fang Fang
Hematology
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How to check for anemia?

Anemia requires an initial routine blood test, which is a complete blood count. If it indicates a reduction in red blood cell count and a significant decrease in hemoglobin, it suggests anemia. Once anemia is indicated by the complete blood count, further tests are guided by the size of the red blood cell volume. If it is microcytic anemia, common types include iron deficiency anemia and anemia of chronic disease, and tests such as serum iron, ferritin, and tumor markers are needed. If it is normocytic anemia, a bone marrow biopsy is required to rule out aplastic anemia, multiple myeloma, etc. If it is macrocytic anemia, tests for folate and vitamin B12 are needed to exclude myelodysplastic syndrome and megaloblastic anemia, among others.

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Written by Gong Hui
Pediatrics
1min 1sec home-news-image

How to supplement baby's anemia?

The treatment for childhood anemia primarily focuses on addressing the underlying cause. Nutritional anemia is the most common type of anemia in children, which includes iron-deficiency anemia and megaloblastic anemia. For iron-deficiency anemia, the main treatment is iron supplementation. This can be done through dietary means, such as increasing the intake of foods high in iron like pork liver and egg yolks. Additionally, treatment should address any underlying causes of iron deficiency. For instance, if parasitic infections are causing blood loss, then treating the parasitic infection is necessary. If the anemia is due to poor dietary habits or picky eating, then changing these habits is crucial. If general treatments are ineffective, then oral iron supplements should be considered. In the case of megaloblastic anemia, it is important to address the vitamin deficiencies that cause it, namely the lack of folate and vitamin B12. Supplementation of folate and vitamin B12 is recommended.