Symptoms of Uremia

Written by Li Liu Sheng
Nephrology
Updated on December 13, 2024
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Once diagnosed with uremia, patients exhibit numerous clinical symptoms, though these symptoms are not completely identical across different individuals. Typically, the primary symptoms of uremia include nausea, vomiting, loss of appetite, with these symptoms becoming more pronounced after eating. There might even be diarrhea, an increase in the frequency of bowel movements, and gastrointestinal bleeding. Additionally, patients show signs of edema, particularly around the eyelids and face, with very noticeable swelling in the lower limbs. Severe cases may also present with pleural effusion and ascites, accompanied by a reduction in urine output. Patients may also experience dizziness, headache, elevated blood pressure, and even exhibit pallor, anemia, itchy skin, bone pain, and intolerance to cold, among various other clinical symptoms.

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Written by Li Liu Sheng
Nephrology
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Does uremia cause fever in its early stages?

Fever is not an early clinical manifestation in patients with uremia; therefore, patients in the early stages of uremia do not exhibit fever. Typically, in the early stages of uremia, patients only show symptoms such as fatigue, poor spirit, lack of appetite, and easy fatigue, and may experience edema, such as swelling of the eyes and facial area after waking up in the morning, making it difficult for patients to open their eyes, and swelling of the lower limbs. In addition, patients also exhibit high blood pressure, such as increased systolic and diastolic pressures, which are difficult to control. Patients often exhibit clinical symptoms such as dizziness and headache. Patients also experience a significant increase in the frequency of urination at night and an increase in urine output, which are all early manifestations of uremia.

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Written by Guan Hai Fang
Urology
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Is uremia cancer?

Uremia is not cancer. Chronic kidney failure refers to the presence of various kidney diseases that lead to a progressive and irreversible decline in kidney function, culminating in a series of symptoms and metabolic disorders that form a clinical syndrome, commonly known as chronic kidney failure. The end stage of chronic kidney failure is what is often referred to as uremia. Uremia is not a separate disease, but a clinical syndrome common to various late-stage kidney diseases. It is a symptom consisting of a series of clinical manifestations that occur when chronic kidney failure enters its terminal stage. Typically, this includes disturbances in water and electrolyte acid-base metabolism, with metabolic acidosis and water-electrolyte imbalance being the most common.

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Written by Wang Li Bing
Intensive Care Medicine Department
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What causes uremia?

Uremia is very common in clinical practice. It is mainly caused by abnormal kidney functions, leading to abnormalities in glomerular filtration, as well as in the reabsorption and secretion functions of the renal tubules, which results in a series of symptoms. Once uremia occurs, it can disrupt the internal environment of the body, cause electrolyte abnormalities, and even lead to life-threatening arrhythmias. Uremia is very dangerous in clinical practice and often requires regular hemodialysis treatment. Therefore, once uremia occurs, medical attention must be sought promptly.

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Written by Zou De Bo
Urology
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Can holding urine cause uremia?

Generally speaking, holding urine does not lead to uremia, but if the bladder is overfilled, it can result in an inability to urinate. This can lead to acute renal dysfunction. After catheterization, the indicators of renal function can quickly return to normal. Therefore, we should try to avoid holding urine as much as possible and go to the bathroom promptly when we need to. This is something we should pay attention to in our daily lives.

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Written by Guan Hai Fang
Urology
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Is uremia serious?

Uremia is very serious. For patients with uremia who wish to be cured, the current method is to undergo kidney transplantation. Kidney transplantation is currently considered the best method for treating uremia. If no suitable kidney source is found, or economic conditions do not allow, or for some other reasons, it is recommended that patients undergo dialysis. Dialysis is also quite expensive, but if economic conditions permit, and physical health and mood among other factors allow, patients with uremia who undergo regular dialysis can generally have their lives extended by several years. It is not uncommon to see reports of lives being extended by more than a decade.