Symptoms of Uremia

Written by Li Liu Sheng
Nephrology
Updated on December 13, 2024
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Once diagnosed with uremia, patients exhibit numerous clinical symptoms, though these symptoms are not completely identical across different individuals. Typically, the primary symptoms of uremia include nausea, vomiting, loss of appetite, with these symptoms becoming more pronounced after eating. There might even be diarrhea, an increase in the frequency of bowel movements, and gastrointestinal bleeding. Additionally, patients show signs of edema, particularly around the eyelids and face, with very noticeable swelling in the lower limbs. Severe cases may also present with pleural effusion and ascites, accompanied by a reduction in urine output. Patients may also experience dizziness, headache, elevated blood pressure, and even exhibit pallor, anemia, itchy skin, bone pain, and intolerance to cold, among various other clinical symptoms.

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Written by Li Liu Sheng
Nephrology
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Causes of Uremia

Uremia is a syndrome caused by the progressive development of various chronic kidney diseases that ultimately leads to bilateral renal failure in patients, unable to timely remove excess water, electrolytes, and various toxins from the body. The causes of uremia are many and complex. Common causes include chronic nephritis, diabetic nephropathy, and hypertensive nephropathy. Other diseases such as chronic interstitial nephritis, chronic pyelonephritis, uric acid nephropathy, chronic obstructive nephropathy, renal vascular diseases, and hereditary nephritis can also lead to uremia. Once uremia occurs, patients often exhibit symptoms of general discomfort and may need to choose dialysis treatment, which can be either hemodialysis or peritoneal dialysis, depending on individual circumstances.

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Written by Zou De Bo
Urology
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Can holding urine cause uremia?

Generally speaking, holding urine does not lead to uremia, but if the bladder is overfilled, it can result in an inability to urinate. This can lead to acute renal dysfunction. After catheterization, the indicators of renal function can quickly return to normal. Therefore, we should try to avoid holding urine as much as possible and go to the bathroom promptly when we need to. This is something we should pay attention to in our daily lives.

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Written by Wang Li Bing
Intensive Care Medicine Department
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What causes uremia?

Uremia is very common in clinical practice. It is mainly caused by abnormal kidney functions, leading to abnormalities in glomerular filtration, as well as in the reabsorption and secretion functions of the renal tubules, which results in a series of symptoms. Once uremia occurs, it can disrupt the internal environment of the body, cause electrolyte abnormalities, and even lead to life-threatening arrhythmias. Uremia is very dangerous in clinical practice and often requires regular hemodialysis treatment. Therefore, once uremia occurs, medical attention must be sought promptly.

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Written by Huang Feng Fei
Urology
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Why would someone get uremia?

Uremia, also known as end-stage renal failure, has many causes. Common surgical conditions include urological obstructions such as urethral blockage, kidney tumors, malformations, kidney cancer, and others, as well as numerous kidney cysts, all of which can lead to renal failure. Common internal medicine causes include chronic glomerulonephritis, long-standing hypertension, hypertensive nephropathy, diabetes, diabetic nephropathy, etc., which can also lead to renal failure. In summary, end-stage renal failure is referred to as uremia.

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Written by Zhou Qi
Nephrology
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Is uremia contagious?

Strictly speaking, uremia is not an independent disease and it is not contagious. Uremia refers to the state where numerous causes chronically damage the kidneys over a long period, eventually leading to the destruction of most kidney tissue, resulting in the kidneys' inability to excrete metabolic waste. There are many causes of uremia, including chronic nephritis, diabetes hypertension, systemic lupus erythematosus, urinary system stones, and even prostate hyperplasia, among others, which damage the kidneys and lead to this condition. Generally, these causes are not contagious as they do not involve bacteria, viruses, or fungi. However, if uremia is caused by infectious diseases, such as hepatitis B virus or HIV, these infectious diseases can be contagious, but uremia itself is not contagious.