The etiology of acute appendicitis

Written by Ren Zheng Xin
Gastroenterology
Updated on September 21, 2024
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The main cause of acute appendicitis is due to the narrowing of the appendiceal lumen, which can easily lead to the obstruction of food residues and fecal masses. Following the obstruction, mucosal damage occurs, which leads to secondary infections. Additionally, neglecting regular living habits, such as overeating, excessive fatigue, and frequent heavy drinking can exacerbate or trigger acute appendicitis. Therefore, maintaining regular living habits in daily life, such as having meals at fixed times, reasonable rest and work schedules, balancing work and leisure, and engaging in appropriate outdoor activities, can play a positive role in preventing acute appendicitis.

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Written by Ren Zheng Xin
Gastroenterology
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Early symptoms of acute appendicitis

The symptoms of the early stage of acute appendicitis primarily include vague abdominal pain, initially across the abdomen, then transitioning around the belly button, and after several hours, shifting to the lower right abdomen where the pain becomes localized. The early symptoms of acute appendicitis are not typically distinctive, with the onset being quite sudden, accompanied by severe abdominal pain, vomiting, and fever. Based on these typical clinical manifestations, diagnosing acute appendicitis is not difficult. Clinically, the main treatment is the surgical removal of the appendix, with laparoscopic appendectomy being the more common practice nowadays. This method involves less bleeding during the operation and a quicker post-operative recovery.

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Written by Ren Zheng Xin
Gastroenterology
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How is acute appendicitis diagnosed?

The diagnosis of acute appendicitis is primarily based on clinical symptoms, signs, and auxiliary examinations. The patient describes abdominal pain accompanied by nausea and vomiting. During the physical examination, migratory pain in the lower right abdomen and significant rebound tenderness upon palpation are noted. Additionally, ultrasound diagnostics suggest swelling of the appendix lumen, all indicative of acute appendicitis. For acute appendicitis, once confirmed, surgery is generally required to remove the appendix, which is the only way to completely cure acute appendicitis.

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Written by Li Jin Quan
General Surgery
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The difference between chronic appendicitis and acute appendicitis

The difference between chronic appendicitis and acute appendicitis is that most cases of chronic appendicitis are formed after the treatment of acute appendicitis. Chronic appendicitis and acute appendicitis display different symptoms. Acute appendicitis has typical migratory pain in the lower right abdomen, which initially appears in the upper abdomen and then moves to McBurney's point in the lower right abdomen. Chronic appendicitis, on the other hand, often lacks upper abdominal pain and initially presents with fixed discomfort or vague pain in the lower right abdomen. Only when chronic appendicitis acutely flares up does significant tenderness in the lower right abdomen occur, and rebound pain appears with peritonitis. Chronic appendicitis may also occasionally present with gastrointestinal symptoms such as nausea and vomiting.

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Written by Ren Zheng Xin
Gastroenterology
45sec home-news-image

The etiology of acute appendicitis

The main cause of acute appendicitis is due to the narrowing of the appendiceal lumen, which can easily lead to the obstruction of food residues and fecal masses. Following the obstruction, mucosal damage occurs, which leads to secondary infections. Additionally, neglecting regular living habits, such as overeating, excessive fatigue, and frequent heavy drinking can exacerbate or trigger acute appendicitis. Therefore, maintaining regular living habits in daily life, such as having meals at fixed times, reasonable rest and work schedules, balancing work and leisure, and engaging in appropriate outdoor activities, can play a positive role in preventing acute appendicitis.

doctor image
home-news-image
Written by Ren Zheng Xin
Gastroenterology
46sec home-news-image

Acute Appendicitis Etiology

The cause of acute appendicitis is primarily bacterial infection of the appendiceal lumen due to various reasons. The appendix itself is a narrow tube connected to the cecum. If a fecalith falls into the lumen, it can cause obstruction of the appendiceal lumen, leading to an increase in intra-luminal pressure and circulatory disturbances in the appendiceal wall. At this time, the mucosa is susceptible to damage, and bacterial invasion of the wall can cause infections of varying degrees. Additionally, gastrointestinal dysfunction, such as diarrhea or constipation, can also cause spasms of the appendiceal vessels, leading to blood supply disturbances and resulting in acute inflammation.